Mitzo, Remicade is an engineered drug originally developed to treat rheumatoid arthritis, now also used for a number of other auto-immune diseases including Crohn's and UC. Its generic name is inflixamib. It is an anti-tumor necrosing factor, a type of antibody. It's given every six or eight weeks through an IV infusion. Because it is very expensive, usually all of the more standard treatments (5-ASA's of different types and by different routes, steroids, immunosuppressants, etc.) are tried before it. For some of us it has been a godsend, for others it hasn't really helped. It put me into a remission when I couldn't get there with any combination of other drugs. I had gotten to the point of considering surgery after a four-year flare.
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Intolerant to Asacol and rectal mesalamine preparations.
On Prednisone then Entocort 2001-2006 with only short periods off.
Current meds are Colazal, Azathioprine and Remicade.
In remission since April, 2006. Remicade has been my wonder drug.