Quincy....pred and 5asa interference

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texasyankee
Regular Member


Date Joined Dec 2007
Total Posts : 28
   Posted 1/1/2008 4:53 PM (GMT -7)   
Is it your observation that prednisone affects the benefits of the Rowasa enamas?  It has been 15 years since I have had to use prednisone but because my flare was not responding to Rowasa the GI suggestd a jump start to kick me into reversal.  I really dislike the side effects of the prednisone....feel like I am floating, hands and legs get shakey, but wold love to have my appetite come back.  I found your comment about the lazy colon interesting (as posted to supernurse in the IBS/UC string).  I have a strong food=pain paradigm so it is easy to avoid eating.  Of course going from 107 lbs to 95 lbs in 3 weeks isn't giving me a strong empowered feeling either.  I am wondering what you suggest as far as foods to eat to start strengthening the colon and giving it the workout it needs?
Thanks for your thoughtful comments.
DXed with left sided UC in 1983 at 20 years of age
-Used prednisone for long periods in the early years (1983-1992) which resulted in severe osteoporosis
-remission through two pregnancies 1993/94 and 1996/97 no meds taken other than prenatal vitamins
-flare in 2000 didn't respond to methasalazane supps or enemas tried methatrexate; mostly in remission for 7 years
-July 2007 new flare with additional never before seen symptoms.....hormone related?, not responding to meds
 
 
 


quincy
Elite Member


Date Joined May 2003
Total Posts : 29843
   Posted 1/1/2008 9:58 PM (GMT -7)   
Hi...I'm never short of comments ;-)

Are you not using any oral 5ASA meds?

There are antispasmodics that can help equalise the rhythm of the colon when eating is a factor.....if you haven't tried them, I suggest you at least do. Low dosge 10mg dicyclomine to start taken as needed.

I've never been on prednisone and was only on steroid foam eneas for one stint of 2 weeks...18 years ago, but in the many years of being on different forums, there is definitely a strong, strong tendency for doctors to put patients on pred firstly and then when 5ASA meds are used afterward. ...it's like starting over from square one. There's something that seems to blow the process, although I don't understand it. I had presented that in another forum about 7 years ago to another member....he had some information on it, but I don't remember exactly the what/why. It leaned toward the negs of using pred with the 5ASA....not being useful for the 5ASA's effect. I think if you need a kick-start, try a short tapering to off- course of it...maybe over a period of two weeks.

I definitely support the fibre/probiotic line of supplements to be taken. I don't use a lot of fibre supplements (recently tried the chia, but I don't think high omegs 3's agree with me somehow..must try them again once this flare is over), but will have to find what gives me the least amount of discomfort. I do support eating for comfort, but I disagree with encouraging the colon to become lazy. common sense has to come into play more than having lots of rules and being afraid to eat.

Your weight has definitely plummeted too far....what exactly are you eating throughout the day? What are you afraid of eating?

I do agree that hormonal flutuations will affect UC...bigtime...and if you suspect perimenopause, get checked out to see if you are indeed going through it. Maybe the doc can offer other meds to see if it helps.

Hang tough....there are also other meds that can maybe used such as the Remicade. Maybe not continual, but as the kick rather than pred.

quincy
*Heather*Status: mini flare Dec 28... increased enemas to nightly
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals/supplements 
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....bromelain 1 - 2x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!

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