Is Colazal as good as Asacol or Sulfasalazine

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Regular Member

Date Joined Jan 2005
Total Posts : 24
   Posted 1/5/2008 12:45 AM (GMT -6)   
Hi all,

I've been on 3g of sulfasalazine and 1g of Canasa for about two years now and was in remission on it. For the past week, though, I've noticed a lot of mucous and a bit of blood on the toilet paper :-( Was hoping it was only holiday stress, but am definitely getting worried now and plan on setting up an appt with my GI on Monday. I'm wondering if maybe the sulfa just isn't working for me anymore? This happened to me with Asacol when I first started using that med. It worked for about a year, than unexplainable stopped, so my GI put my on the sulfa. Does this happen often with the drugs?! and if my GI puts me on Colazal, is it like Asacol or sulfa? I've been trying to find some info on where Colazal is release in the colon and other info, but I've been having a hard time. Any thoughts would be appreciated. Thanks!

-Sulfasalazine (6 daily) + 1 Canasa nightly
-Primadophilus Reuteri

Old Hat
Veteran Member

Date Joined Feb 2007
Total Posts : 5187
   Posted 1/5/2008 12:08 PM (GMT -6)   
For some of us Colazal has worked better than the older oral 5ASAs, Azulfidine, Asacol, or Dipentum, or Pentasa. So it is likely worthwhile for you to give it a try for a month or 2 to be able to gauge any differences. / Old Hat (nearly 30 yrs with left-sided UC; currently on 3 Colazal daily for maintenance of remission)
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