canasa-loose stools?

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Regular Member

Date Joined Nov 2007
Total Posts : 390
   Posted 1/7/2008 9:07 AM (GMT -6)   
my daughter is finding that her stools have been loose in the last few days, it began before she went to the court enema every other night from every night- she believes it's because it's the canasa 3x daily, there is no blood and no more urgency or frequency, but she has made a concerted effort to get that 3rd suppossitory in . could these be causing loose stools?
Mom to 19 year old daughter diagnosed 11/07.
asacol 2 3x daily
colazal 3 3x daily
proctofoam 3x daily
mesalamine enema 1x daily
canasa suppostiories 3x daily (usually doesn't get to do 3)
culturelle probiotic 1 daily
chewable vitamin
hydrocortisone enema at bed tme

Old Hat
Veteran Member

Date Joined Feb 2007
Total Posts : 5185
   Posted 1/7/2008 12:01 PM (GMT -6)   
In my experience Colazal is the 5-ASA med that does the most to solidify bms. I personally detest Canasa; it is greasy because of the fatty esters used to bind the med, etc. (Probably the pharmaceuticals make a lot of money on it so they keep pushing it at patients; one member wrote to another thread recently that it cost him "$10 a pop"!) As your daughter tapers the Cortenema she is still using mesalamine enemas, right? I don't think it's necessary to use both the mesalamine enemas AND Canasa since her symptoms have come under control. She'll probably be able to manage with the oral meds & mesalamine enemas together. The mesalamine enemas do contain sulfiting agents as a preservative; some patients have problems with that. They're not ideal for solidifying bms, but they do reduce & eventually eliminate UC inflammation for us 5-ASA responders. Hope this explanation helps. There are foods, such as plain boiled rice, that help to solidify bms. Some patients use Metamucil to bulk up their waste; they may reply to your post about it. / Old Hat (nearly 30 yrs with left-sided UC; currently on 3 Colazal daily for maintenance of remission)

Veteran Member

Date Joined Mar 2008
Total Posts : 1766
   Posted 4/17/2008 5:47 PM (GMT -6)   

So I (re)started Canasa last week and it caused diarrhea and cramping Tuesday and Wednesday mornings. My GI nurse told me to go off of it. But this morning I was still having diarrhea and now even blood in my stool. I'm confused as to whether Canasa was helping, harming, or both?

Any insights?

Female, Age 19, Dx w/ UC August 2007
9 Asacol/day, 1000 mg Canasa (caused side effects)

Elite Member

Date Joined May 2003
Total Posts : 30704
   Posted 4/18/2008 12:01 AM (GMT -6)   
ComedyDork..Things can get worse before they get better...I would strongly suggest you try the 5ASA retention enemas if you haven't already.

*Heather*Status: mini flare Dec 28... tapered to every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....zymactive 3 - 5x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!

Veteran Member

Date Joined Mar 2008
Total Posts : 1766
   Posted 4/18/2008 7:12 AM (GMT -6)   

I had tried enemas right after I was diagnosed, but I think it must have given me a fissure or something because it caused more bleeding. Which is why this time I went for the suppository.

Hopefully things will get better once I start probiotics this weekend. At least this morning I don't have bad cramps and diarrhea.

Female, Age 19, Dx w/ UC August 2007
9 Asacol/day, 1000 mg Canasa (caused side effects)

Regular Member

Date Joined Apr 2008
Total Posts : 499
   Posted 4/18/2008 7:20 AM (GMT -6)   
I'm sorry your daughter is having these problems, I was on canasa and my symptoms improved but now I am off of it and just on asacol pills.  When I took canasa I did not experience the bad symptoms.  Good luck.  Bellski
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