6 mp - mercaptopurine

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Regular Member

Date Joined Oct 2007
Total Posts : 348
   Posted 1/7/2008 1:31 PM (GMT -6)   
can anyone give me any info of their experience with 6 mp (mercaptopurine)?  My doctor does not want to keep putting me on prednisone and the asacol just isn't doing the job.  Switched to azulfidine a month ago as that worked well when I was first diagnosed with uc 26 years ago.  Have 4 more cortenemas to do every other night, then back to the mesalamine enemas every other night and hoping that the azulfidine will prove to be doing some good, if not then the doc wants to try me on 6mp...........
diagnosed with uc 27 years ago.
asacol 400 mg 3 tabs 3x a day
hoping for remission soon

Veteran Member

Date Joined Nov 2005
Total Posts : 675
   Posted 1/7/2008 8:43 PM (GMT -6)   
I'm not currently taking 6mp, but took it for about 2 years between 2004 and 2006. I tapered off of prednisone while on 6mp. I took 9 colozal tablets daily and used Canasa daily while on 6MP. It took over 3 months for the drug to start working for me (about 5 months really). I had a monthly blood test while on 6MP. I also started Remicade in December 2005 while on 6MP, as my symptoms didn't improve enough for me. After I was on Remicade for about 9 months I had to stop taking 6MP. I had nausea for the first few months of taking 6mp, but took it at night so as to reduce the nausea. I think fatigue was also my biggest complaint while on 6MP. That being said, for many patients it does the job and works very well. Every patient is different.
pancolitis. Osteopenia. multi-vitamin, calcium, omeprazole, benefiber, boniva. Remicade since Dec. 2005.
"The secret to my own happiness, my own good future, is within my own hands, I must not miss that opportunity"

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