Depends on how sick you are. The first time or two I was on it, I had to start at a higher dose and it took a while to feel better. This last time, with a mild flare, I was started in a moderate dose with an immediate taper and I felt better overnight.
Are you doing anything else to support your health? Supplementing with probiotics to restore good gut ecology, taking omega-3s for inflammation, taking l-glutamine to help control diarrhea... there are alot of things you can do to reduce your need for meds.