I am not sure about what trials are out there, but I wouldn't risk being on a placebo and getting sicker. It seems like the next step medication-wise would be to try Remicade or Humira. Does your daughter ever take anything like Lomotil? It is not a cure, but sometimes when I am having too much D, the lomotil stops it so my poor colon and rectum can rest. Sorry to hear she's not better. Sometimes the medicines just don't work, it's nobody's fault.
Diagnosed with Left-sided Ulcerative Colitis 1995 at 15
Tried: Prednisone, Rowasa & Hydrocortisone Enemas, Proctofoam, Sulfasalazine, Asacol, Probiotics, Fish Oil, Canasa, Enotcort, Colazol, Proctocort, Anamantle, etc...
Diagnosed with Ulcerative Proctitis with almost rectovaginal fistula in 2004, put on Remicade, August 2007:Increased Remicade dosage-700mg every 6 weeks,diagnosed with Psoriatic Arthritis & Fibromyalgia Current meds:
Remicade 700mgs every 6 wks (had reaction, will start Humira Jan 29) Clorazepate, Proctofoam HC, Glucosamine 500, Vitamin B, Lomotil as needed, Darvocet, Tylenol pm