question about ASACOL upset stomach ..and D's

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Regular Member

Date Joined Aug 2004
Total Posts : 79
   Posted 1/15/2008 12:46 PM (GMT -6)   
I just switch from colazal to asacol ...and i am having stomach pain ....trips to the bathroom
i just got a new drug coverage and they wont cover colazaL ...but will cover asacol untill the generic hits the streets i will be on asacol .
My question is this did any of you expierence this and was it temporary ....please help ...thanks 
REMIDCADE 10-02-07
colazal 750mg 3x3 a day
mercaptopurine 50mg 1 a day
allopurinol 100 mg
rowasa enema pm
multi vitamin
folic acid
fish oil
dx 2004 uc

Regular Member

Date Joined Jul 2007
Total Posts : 402
   Posted 1/15/2008 12:58 PM (GMT -6)   
I did not experience any of that with Asacol. No side effects from day one. What about Lialda? Would that be an option under your insurance?
Current Medications:
- Asacol (4 pills, 3x per day)
- Rowasa (1 enema daily, as needed)
- Folic Acid (1 mg, 1x per day)
- Calcium (600 mg, 2x per day)
- Prenatal Vitamin (1x per day)
- Iron (2x per day)

Veteran Member

Date Joined Aug 2007
Total Posts : 2204
   Posted 1/15/2008 1:35 PM (GMT -6)   
Side effects of Asacol from WebMD:

Flu-like symptoms, vomiting, nausea, dizziness, weakness, headache, constipation, abdominal/back pain, upset stomach, diarrhea, or gas may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Alot of folks have problems with Asacol. If yours continue, talk to your doc about switching back or to something else.
Diagnosed with ulcerative colitis spring 1999
Therapeutic dose sulfasalazine.
Probiotics, l-glutamine and fish oil caps. George's aloe vera juice and Mucosaheal.

potty girl
Veteran Member

Date Joined Dec 2006
Total Posts : 835
   Posted 1/15/2008 7:23 PM (GMT -6)   
When I first started takeing asacol I would get a little stomach pain but it didnt last very long maybe a week are so and the pain for me wasnt all the time just every now and then threw the day. hopefully it will get better,

synthroid .088 mg, lowpressor 50 mg x 2, cozaar 25mg x2, imdur 30 mg
nitroquick, proventol, plavix 75 mg, protonix 40 mg x 2, asacal 400mg x 9
carafate 1 gm x 4, zyrtec 10 mg, rhinocort aqua nose spray, fish oil,

Veteran Member

Date Joined Jan 2006
Total Posts : 616
   Posted 1/15/2008 7:46 PM (GMT -6)   
I actually had to reduce my asacol intake to get completely into remission.
But there are many people who can't tolerate Asacol, so maybe give it a few days then discuss it with your GI if you don't improve.
Asacol 4 tabs 2x daily
Forvia once a day
Probiotic twice daily
Methotrexate 3 pills once a week
Actonel once a week
Calcium supp.
1 mg Folic Acid daily
Omega-3 once daily
Eleventh Remicade infusion End of January

Regular Member

Date Joined Oct 2007
Total Posts : 320
   Posted 1/15/2008 9:36 PM (GMT -6)   
I had to move over to Colazide (Australian name for Colazal) because the standard 5-ASA drugs like Asacol made me feel sick in the stomach and made my D far, FAR worse. This never improved for me.

Best thing that ever happened was to move over purely to Colazide. I pay for it, but its so many kinds of worth it!
"We are dreamers, shapers, singers and makers..." - Elric, elder Technomage
    - 2xColazide, twice a day; 1x6-mp twice a day; 1xAbatacept 10mg/kg per month;
    - 1xZinc per day, 2xScoop of Sustagen Sport per day;
    - 1xBIOCeuticals UltraBiotic 45 per day, 1xBIOCeuticals SB FlorActiv per day;
    - 1xHeaped teaspoon of Metamucil smooth orange powder 3 times a day.

Regular Member

Date Joined Aug 2004
Total Posts : 79
   Posted 1/15/2008 10:12 PM (GMT -6)   
Thank you all for your replies

I am filling better already i posted after i took my first four pills ....seems to be getting better ...i go see my GI in two days ...and in two weeks i will get my 4 remicade infusion :-) :-)
REMIDCADE 10-02-07
colazal 750mg 3x3 a day
mercaptopurine 50mg 1 a day
allopurinol 100 mg
rowasa enema pm
multi vitamin
folic acid
fish oil
dx 2004 uc

Veteran Member

Date Joined Jul 2005
Total Posts : 514
   Posted 1/15/2008 10:31 PM (GMT -6)   
Don't know how many you are taking, but you might try taking smaller doses throughout the day instead of 4 at once and also try to eat something with them. When I first started taking them I couldn't take too many at a time(I am on only 6 a day, my doc said to take 3 twice a day, I broke them up to 2 3 times a day). That only lasted a couple of weeks and now I can take all 6 at once with no side effects.
Officially Diagnosed with UC in June 2003.  Have had stomach issues since 1989.  Unknown if they are related or not.  Have mild/moderate UC.  Have had 4 flares, the last one caused by hormones from stopping breastfeeding.  Currently back in remission!  Only taking 6 Asacol a day.   Will take Rowasa enemas as needed. Colozal did not work for me.  Luckily my UC is relatively minor and responds well to meds, but man do those flares hurt!

Veteran Member

Date Joined May 2007
Total Posts : 528
   Posted 1/16/2008 9:16 AM (GMT -6)   
I just switched off asacol yesterday. I was taking 3 pills, 4 times a day, and for 10 months I had absolutely no problems. about 2 weeks ago I started having lots of nauseous, and my GI thought it might be the asacol. my GI said that some people's D does worsen on asacol, so you should keep an eye on it. It might be that this passes once your body adjusts to it, or it might be that you just can't tolerate it. I will say that within 24 hours of switching off Asacol to Colazal I feel much better. no nausous. so, just watch it.

also, I don't know what your GI is like, but given that colazal is supposed to come off patent soon, would he/she be willing to just give you some free for a month or 2, to hold you over, if it turns out colazal works better? maybe they can provide you the drug just until it gets out on generic??? just a thought. The GIs get so so so much of this stuff via samples that yours might have some to spare... never hurts to ask.
Pancolitis dx 3/07
9 Colazal a day (used to be on 12 Asacol, don't think Asacol helped)
150mg Imuran/day (steroid dependent, reached this dose 9/07)
Various vitamins, bit of fish oil, a probiotic.

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