can Colazal help this quickly??

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Veteran Member

Date Joined May 2007
Total Posts : 528
   Posted 1/16/2008 9:34 AM (GMT -6)   
Yesterday morning I saw my GI. I have been nauseous, having frequency and urgency, and just really not feeling very well, not eating that much. He switched me off Asacol to Colzal and today, literally exactly 24 hours and 4 doses of Colazal later, I feel so much better. Not all symptoms are gone, but my appetite is returning, and I am less exhausted. My GI had said that the Asacol could be making me sick, so it might just be getting off Asacol that helped, but he also said that Colazal could make me feel better in as little as 2 days, if it was a good drug for me. But, I just didn't believe him. I guess I figured that if I need Imuran, how can a milder drug be of any use to me. But, maybe I am wrong??? Have any of you has such a dramatic and quick turn around on Colazal? thanks.
Pancolitis dx 3/07
9 Colazal a day (used to be on 12 Asacol, don't think Asacol helped)
150mg Imuran/day (steroid dependent, reached this dose 9/07)
Various vitamins, bit of fish oil, a probiotic.

Veteran Member

Date Joined Apr 2006
Total Posts : 3402
   Posted 1/16/2008 9:37 AM (GMT -6)   
I had something similar happen when I stopped Colazal and switched to Asacol in 2003. I think it was about 48 hours to a major difference.

Shows how individual this disease can be!
Pan-colitis and GERD diagnosed May 2003
Asacol 12 per day,  Azathioprine 75mg, Aciphex, Effexor XR, Forvia and a Probiotic
Osteopenia (hip and spine) from prednisone use.  Started Azathioprine because I was steroid dependent.
Co-Mod for the UC forum
Keep HealingWell running smoothly:

Elite Member

Date Joined May 2003
Total Posts : 30999
   Posted 1/16/2008 10:38 AM (GMT -6)   
Sounds good to me!
*Heather*Status: mini flare Dec 28... increased enemas to nightly
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....bromelain 1 - 2x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!

Veteran Member

Date Joined Jul 2005
Total Posts : 514
   Posted 1/16/2008 3:58 PM (GMT -6)   
Yup, colozal did nothing for me and within 24 hours of starting Asacol I started feeling better(after having a mild flare for 2 months) and after a few days I was back in remission. It is my wonder least for now! Everyone is different. I took colozal for months with no results. And those pills are so HUGE. I like my tiny Asacol pills. = )
Officially Diagnosed with UC in June 2003.  Have had stomach issues since 1989.  Unknown if they are related or not.  Have mild/moderate UC.  Have had 4 flares, the last one caused by hormones from stopping breastfeeding.  Currently back in remission!  Only taking 6 Asacol a day.   Will take Rowasa enemas as needed. Colozal did not work for me.  Luckily my UC is relatively minor and responds well to meds, but man do those flares hurt!

Old Hat
Veteran Member

Date Joined Feb 2007
Total Posts : 5191
   Posted 1/16/2008 5:55 PM (GMT -6)   
Colazal was MY big break-through in UC treatment! Asacol did not agree with me; it's supposed to start dissolving in the terminal ileum & is said to require a certain pH level to disperse in the most beneficial way. Colazal breaks down inside the colon, which seems better for many of us UCers. Great to read that you're already feeling much improved!!!!!!!! / Old Hat (nearly 30 yrs with left-sided UC ... [etc.])
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