Well, it's reassuring to hear that others have to deal with the trials and tribulations of prednisone. I'm on my first course ever. The doc started me at 20 mg, but I got worse, so I went up to 30mg. Tomorrow, after 11 days at 30 mg, I'll call and see if I can taper the dose to 25 mg for a week, then 5 mg/wk until 0. I'm still not symptom free. My main symptom is rectal bleeding. I'd love for that to go away. It's diminishing, but not gone. Does anyone struggle with constipation rather than diarrhea?