New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Regular Member

Date Joined Aug 2007
Total Posts : 25
   Posted 1/22/2008 12:35 PM (GMT -6)   
Anyone have their docs prescribe antidepressants?  My doctor wants to prescribe LExapro - anyone on it?  Side effects I should be aware of?
Diagnosed UC June 2007 (mis-diagnosed with IBS for 3 years)
Current meds: Asacol 9 12/day, Prednisone 10 mg (YAYYY!), Prilosec 40mg, fish oil, iron, multivitamin, probiotic.
6-MP 25mg 75mg, Cortenema

Regular Member

Date Joined Aug 2007
Total Posts : 277
   Posted 1/22/2008 12:41 PM (GMT -6)   
my husband takes lexapro, i take zoloft. He doesnt have any side effects
lower left UC diagnosed 1991
Asacal, zoloft, levoxyl, prednisone 40m 30m 25m 40m, 35m, multi vitamin, Azathioprine 100m (started 1/9/08)

Veteran Member

Date Joined Apr 2006
Total Posts : 3402
   Posted 1/22/2008 2:28 PM (GMT -6)   
I'm not sure I'm clear on what your doctor is prescribing ADs for...

Are you depressed? Depression is common with chronic illness.

Sorry, haven't used Lexapro. You can check the side effect possiblities at
Pan-colitis and GERD diagnosed May 2003
Asacol 12 per day,  Azathioprine 75mg, Aciphex, Effexor XR, Forvia and a Probiotic
Osteopenia (hip and spine) from prednisone use.  Started Azathioprine because I was steroid dependent.
Co-Mod for the UC forum
Keep HealingWell running smoothly:

Regular Member

Date Joined Aug 2007
Total Posts : 25
   Posted 1/22/2008 2:32 PM (GMT -6)   
I guess she feels I'm mildly depressed from dealing with all this UC stuff and it taking so long to get into a remission, big weight gain from all the meds, etc..  I'm just generally all around frustrated at the entire situation, but she thinks I'd benefit from a boost in the mental department :)

Diagnosed UC June 2007 (mis-diagnosed with IBS for 3 years)
Current meds: Asacol 9 12/day, Prednisone 10 mg (YAYYY!), Prilosec 40mgfish oil, iron, multivitamin, probiotic.
6-MP 25mg 75mg 50mg, Cortenema, Remicade

Regular Member

Date Joined Dec 2007
Total Posts : 102
   Posted 1/22/2008 3:10 PM (GMT -6)   

 Iwas just diagnosed with Crohn's Colitis (GI says could be UC but more like Crohn's) on Jan. 10, 2008. I started having major depression and fatigue a couple of months before I knew I had Crohn's. At the time I didn't make the connection. I first tried Cymbalta but it made me feel too sick, it works very well for some people everyone is different. Then I went on Lexapro and it made all the difference in the world. I started feeling better after only a few days, some antidepressants take a month or more to start working. I found the best way to keep it in ypor system evenly so you do get too drowsy or insomnia or something until you are really used to it ( is still do it anyway) Is to break the pill in half and take each half approx. 12 hours apart. I just started my Crohn's/UC treatment a week ago with Colocort rectal hydrocortisone enema every night before bed. It instantly made a huge difference in how I feel, mainly the horrible fatigue has gone. Now I know that all these things are connected. I have struggled with digestive troubles for years and I thought I just had IBS or something. Little did I know! But of all the symptoms that I've been dealing with, the depression was by far the worst of all, it knocked me on my butt. When you are depressed life just doesn’t seem to even have a point to it. So in my opinion the antidepressant is very very important part of treatment. Sometimes you have to try a few to find the right one for you. Lexapro works great for me with very few side effects. I take 10mg a day, broken in half 5mg when I wake up and 5mg around 6 or 7 at night. You don't want to take it right before bed because it can cause you to not be able to go back to sleep if you wake up in the night. At least till you are used to it for a while. I don't know which group I belong in Crohn’s or UC.  My entire colon has patches of inflammation but the worst is the recto-sigmoid area.   Only the colon is involved.  I will be posting about my Colocort because it is a UC med and no one on the Crohn’s forum knew much about it.  I have many questions. I hope the Lexapro helps   depression.  When you feel emotionally stronger it makes it so much easier to cope with the physical parts of this disease.  Good luck and take care.


smurf  debbikay

Post Edited (debbikay) : 1/22/2008 1:39:27 PM (GMT-7)

Regular Member

Date Joined Nov 2007
Total Posts : 30
   Posted 1/22/2008 3:44 PM (GMT -6)   
My husband takes Lexapro..I dont think it does him any good.hes still mean! I take paxal-have been for 8 years now. I think it has helped alot.

Regular Member

Date Joined Jan 2008
Total Posts : 27
   Posted 1/22/2008 4:10 PM (GMT -6)   
I have been on 3 different anti-depressants due to my depression. This was before I had colitis. None of them fixed my depression and I ended up addicted and went through hell trying to get off one in particular (Paxil). I am very much against anti-depressants unless they are absolutely necessary. I am no doctor but this is just my opinion. Anti-depressants do not fix the cause but just deal with the symptoms. I personally recommend meditation, it is extremely powerful the better you get at it. I was also extremely tired while being on anti-depressants as well. "In my opinion" the cause of depression can be a number of things but I believe happiness can be found through taking care of your well-being physically, mentally, emotionally, and spiritually.  Things like meditation or yoga I think are the best things to keep your spirits up! Just make sure you look at all points of view before making a decision. :) Good luck!

Chris 21/M
Diagnosed Sept. 07
Salofalk 500mg plus nightly enema
Steroid enema
Fish Oil, Multivitamin
Status: 1-3 BMs a day. Each one D or lose and each one urgent!

Veteran Member

Date Joined Feb 2007
Total Posts : 640
   Posted 1/22/2008 4:21 PM (GMT -6)   
Nothing in my life has been as much of a complete struggle as my depression. I have very mild and easily controlled colitis, so I know that I am blessed (very blessed) in that regard. My depression was an abyss from which I could not escape until Effexor. I have gained control over my thinking. I have gotten MYSELF back.

I do not like having to take antidepressants, but I've gone through lots and lots of therapy, and one of the biggest components to my depression was my whacked out thinking. No matter how hard I tried to be upbeat, positive, tried to implement suggestions of my therapist to effectively handle my depression, it was as if my brain would wrest control from me, telling me all kinds of hopeless and awful things (untrue things!!!) about me and my life, and soon I was spiraling further and further downward into the hell on Earth that depression is.

I would cycle through that by crying myself to sleep, not answering the phone, locking the doors, spending hours literally beating myself up, and upon waking, would vow to never, ever repeat such a horrible thing again, only to have it happen again and again. I needed more help than meditation and insight. I needed something to stop my brain from that kind of awful, awful, hurtful, FALSE thinking. Effexor does that for me.

I hope that one day they will figure out what causes depression and help sufferers fix that problem in a way that does not involve medication. Until then, I say fight it with everything you've got. It is, after all, your life you're talking about, and if you're spending much of that life feeling depressed, sad and suicidal, or if you're unable to do the things you want to do because you have UC and can't be more than steps from the bathroom, fight. Fight for yourself. Time will march on. There's too much living to be done to allow that to happen, as far as I'm concerned.

Good luck to you!

Sporadic proctitis since about 1985. Mother had J-pouch surgery 1983.
DX'd with clostridium difficile in 2000. Pred, two courses of Flagyl, then Vancomycin finally got rid of it. 2001 colonoscopy dx'd left-sided UC. . Treated with prednisone, Rowasa, Asacol. Asacol not working, switched to Imuran. Three small flares since in 2002, 2005, and 2007, brought under control with steroid and Rowasa enemas. Lap Chole performed October 26, 2007, after gall bladder attack in June, '07.
Daily meds: 100 mg Azathioprine and 225 mg Effexor XR (for chronic, longstanding depression), many vitamins and Primadophilus Reuteri

Regular Member

Date Joined Jun 2007
Total Posts : 364
   Posted 1/22/2008 8:47 PM (GMT -6)   
My son had been sick for a year with what ended up being his worst flare followed by my daughter's dx shortly there after, and I hit rock bottom. I couldn't eat, couldn't sleep and lost weight. Dr. rx'd Lexapro and it helped very quickly. I'd say my main side effects are sleepiness and lack of motivation and some jaw tension/headaches - not too bad if I focus on relaxing. I myself don't have UC so I can't comment on how if effects that. I have regained the weight I lost and so far haven't gone above and beyond that, so I don't think it causes weight gain.

I hope you are feeling better both physically and emotionally very soon. UC and depression are just the pits!!
Julie - Mom of Son 16 UC dx 07/02, Sulfasalazine, Imuran, folic acid, L. Reuteri, Zyrtec, Iron, Biotin, Vit/Min
& Daughter 8 UC dx 08/07 Colazal, Prednisone, 6MP, Iron, Vit/Min.

Veteran Member

Date Joined May 2006
Total Posts : 619
   Posted 1/24/2008 4:53 PM (GMT -6)   
I'm on Lexapro. It's effects are pretty subtle, mainly I don't cry all the time any more. So I guess it's beneficial :-)

My GI prescribed it because on top of not being able to get into remission and off the Prednisone, since last August we've been dealing with my daughter's major clinical depression and polysubstance abuse. Since August she has been in juvenile detention, a mental hospital and now a residential treatment center. At the same time I am dealing with that stress, I am trying to get myself into remission -- the Remicade seems promising and we're increasing the frequency of infusions before I try tapering off the Pred.

The Lexapro does seem to be helping, and I also have Xanax to take as needed. With the Prednisone I sometimes get severe agitation, kind of like an "almost panic attack." The Xanax helps with that pretty fast.

A couple of years ago my husband started to get panic attacks and he was prescribed Lexapro and it helped him out very well.

Diagnosed UC April 27, 2006
Remicade infusions: 7/21/07; 8/18/07; 10/13/07; 12/15/97;
Lialda, 4 tabs in the morning; Protonix; Prednisone 4/27/06-present, was almost off, back to 40 mg; 12/1/07 - 12/29/07 weekly Venofer (iron sucrose) injections; 9 mg Entocourt EC; Xanax as needed; Lexipro 10 mg, Rowesa; Asacol; Colazal three 750 mg capsules 3X day; Bad reactions: Imuran( 2/07)

New Member

Date Joined Jan 2008
Total Posts : 14
   Posted 2/4/2008 9:40 PM (GMT -6)   
I have been on Elavil for 20 some years.  My doctor prescribed it when I was diagnosed with IBS saying it would slow my system down, a calming effect.  I have tried Lexapro but discontinued it because I couldn't see any difference in my condition (UC).  I take so many prescriptions that I don't want to increase my intake if not helpful.  My father was taking Lexapro recently & also seeing no improvement so we switched him to Cymbalta which is an anti-depressant & pain killer.  Now he is doing so much better.  He also has IBS & is 91 yrs. old & recently lost his wife of 72 yrs.  Cymbalta has helped him & Lexapro has been the happy pill for our neighbor.  Guess everyone responds differently to meds so try & see what works best for you.

Regular Member

Date Joined Dec 2007
Total Posts : 151
   Posted 2/4/2008 10:09 PM (GMT -6)   
I am begining to wonder if I don't need an anti-depressant.     Lately I have been feeling so fatigued and worthless and hopeless.    In the past,  I had been on anti-depressants,  but was able to be off them for several years (well before this darned UC diagnosis).    I waas thinking that my fatigue and joint pains were related to my last hospitalization and the start of remicade, but now beginning to wonder if more depression thrown on top of it all.    Lately all I do is go to work,  come home,  barely muster up a dinner, and then go lay in bed.   Every night,  thats the highlight of my evening..going to bed.   how sad is that? 
41 yo RN, happily married, with 2 beautiful daughters, Tianna(14 yo) and Alyssa(10 yo).   Diagnosed L sided Ulcerative Colitis in Jan '04 and Diabetes type 2 in June '05.
Remicade infusions ~ 11/6/07, 12/6/07, 12/20/07,  6-MP 100mg daily, Pentasa 500mg twice a day, prednisone 20mg 10mg 5mg daily, Nexium 40mg twice a day, Lantus insulin 45 35 25 units daily, Novolog 10 8 5 units with sliding scale at meals, Amaryl 2mg daily, multi-vitamin daily, Calcium daily, B complex vit daily,  and pro-biotics daily.

Elite Member

Date Joined May 2003
Total Posts : 30828
   Posted 2/5/2008 1:15 AM (GMT -6)   
Hi Christine....does sound as though you are depressed...especially since you mentioned you were on antidepressants in the past.

There's one called Cymbalta that deals with body pain as well...maybe that could be an option for you.

I was prescribed Effexor XR for my depression (not UC-related)...and it's been great. I would think that if you feel tired with no energy....Lexapro or Celexa wouldn't be as good as maybe Wellbutrin or Effexor.
Hope the doctor has some samples for you to try.

Have you had your thyroid checked lately? That could be a huge factor in how you're feeling.

*Heather*Status: mini flare Dec 28... tapered to every second night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....bromelain 1 - 2x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!

Veteran Member

Date Joined Feb 2006
Total Posts : 5698
   Posted 2/5/2008 9:29 AM (GMT -6)   
I was depressed in my last flare with UC and chalked it up to the side effect of prednsone use. I turned down my GI's suggestion of an antidepressant as I felt that since the depression was caused by UC then if I could get in remission I would lose the depression. Sounds good, right? As it turns out about one year post surgery and pred-free for about 10 months I found myself spiraling further downhill. I finally sought a therapist and was prescribed Celexa. As it turns out it was not the prednisone that caused my depression, it was the CHRONIC ILLNESS that I had lived with for over 2 years. My doctor said I would have to stay on the medication to cover the 2.5 years I was sick plus 2 years post surgery. The recipe worked and I was able to wean off Celexa.

I tried all the other treatments, yoga, lots of exercise, eating right, etc. Nothing worked until I went on medication. I wasn't happy about it, I had just gotten off 22 pills per day for UC but in the end it was worth it.

dx proctitis in 1987
dx UC in 1991, was stable until 1998
1998 started prednisone, asacol, pentasa, nortriptylene, ativan, 6MP, rowasa enemas and suppositories, hydrocortisone enemas, tried the SCD diet, being a vegetarian, omega 3s, flax, pranic healing, yoga, acupuncture, probiotics
2000 lost all my B-12 stores and became anemic
2001 opted for j-pouch surgery- now living life med-free

Regular Member

Date Joined May 2006
Total Posts : 304
   Posted 2/19/2008 10:37 PM (GMT -6)   
We are a Zoloft family. We're all on it. I've been on Zoloft for 13 years. Helped me through some very tough times. It totally transformed my husband from being an anxious, depressed man to a wonderful, sweet husband.
  • Pancolitis since 5/06 at age 50, IBS since childhood
  • Degenerative Disc Disease/Spinal Stenosis - L4 and L5
  • Prescribed: Asacol, Atenolol, Zoloft, Synthroid, Menest
  • Prescribed: Xanax & Hydrocodone as needed
  • OTC:  Probiotic 15-35, Multi Vitamin, B Complex, Turmeric, Fish Oil, Biotin

Veteran Member

Date Joined Feb 2005
Total Posts : 1373
   Posted 2/20/2008 12:27 AM (GMT -6)   
Hi Puglover,
   Just chiming in my 2 cents about anti depressants.. I have been on Effexor XR for about 3 years now... It did help me at first, but I do believe now that if I had just stuck it out and tried dealing with things they would have worked out anyways. I don't know your particular situation, but unless you are truly depressed, I would stay as far away from anti depressants as possible. I have tried to get off Effexor Xr 4 times, and have been un-successful.. the withdrawl side effects are HORRID and it can make you very sick ( it did me, all four times so I went back on it ) ANd, I was trying to taper off...  I guess what might help is if you do decide to go on something, just try and keep it at a low dose and for as short a time as possible.. that might make it easier to stop taking it should you ever want to.
  I would suggest doing some research online, it sure opened my eyes... but for me it was too late.  Sorry to be so dreary sounding, but that is my experience and my case only...  I am sure there are many people who have benefited immensly from AD's and in their case it was probably a life-saver drug.. 
  I guess I'm just saying to be careful, and make sure it's something you really really REALLY need..
  Good luck!
Diagnosed with U/C January 31st, 2004, IBS on July 21st, 2006 
Meds: Rowasa enema's- Been off them since leaving Montana, praying I stay off them.
         Bentyl 10mg. As needed - Nexium 40mg. 
         Xanax .5mg as needed - Effexor 37.5mg. - Culturelle 1x a day
    Matthew 11:29   Take my yoke upon you and learn from me, for I am gentle and humble in heart, and you will find rest for your souls.         

New Topic Post Reply Printable Version
Forum Information
Currently it is Wednesday, August 15, 2018 6:11 PM (GMT -6)
There are a total of 2,993,059 posts in 328,014 threads.
View Active Threads

Who's Online
This forum has 161212 registered members. Please welcome our newest member, LymePie.
294 Guest(s), 16 Registered Member(s) are currently online.  Details
GreenBeans, Kent M., Ak123, CashCat, compiler, cashlessclay, Serenity Now, Hoagie, Scaredy Cat, Redwing57, Tudpock18, Hawaii3654, Saipan Paradise, songlady, fjdrill, Steve Smith