Immuran doses....

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Numb78
Regular Member


Date Joined Sep 2007
Total Posts : 63
   Posted 1/25/2008 8:59 AM (GMT -6)   
Hello all, I have just been started on Imuran about a week and a half ago. I am currently seeing one primary GI specialist and another one for a second opinion. My primary doc started me off at 100mg and is only requesting blood tests every 2 months. The second opinion doc is saying that I should be at 150mg given my body weight and wants me to have weekly blood tests.

I'm very confused on what I should be doing? Currently at 100mg I don't think I'm feeling any side effects of the Imuran although I'm also not getting any closer to remission. I know I've read that it takes a long time for imuran to kick in but I've just been in a flare for a long time and am desperate to get things out of control. My question is for those who are one imuran what type of doses are you one and how often is your blood tested?
Currently in a flare since summer 07.
Current Meds: 35mg Pred, 2000mg salofalk, calcium supplements
Just about to start 100mg Imuran.


Scottishcammy
Regular Member


Date Joined Nov 2007
Total Posts : 124
   Posted 1/25/2008 9:02 AM (GMT -6)   
Started on 50mg a week ago. Will get result of enzym blood test next week and, if ok, will move up to 150mg.
Weekly blood tests for first 3 months then monthly.
I think that's pretty standard here in the UK.
Diagnosed Indeterminate Colitis 25/11/2007 (update: told by consultant 15/01/08 in his opinion definitely UC). 1 x Solofalk Enema/day 40mg Prednisolone 35mg Prednisolone 30mg Prednisolone 20mg Prednisolone 25mg Prednisolone 20mg Prednisolone 15mg Prednisolone 4g Pentasa/day

Taken off Pentasa and now on 15mg Prednisolone, Omeprazole 20mg, 2 x Calcium Adcal D3, and started 50mg Azathioprine/Imuran.


Beth75
Veteran Member


Date Joined Jul 2007
Total Posts : 2148
   Posted 1/25/2008 10:10 AM (GMT -6)   
started at 100mg for two weeks then 200 mg since then.

I had weekly blood tests for 4 weeks, then monthly for 3 months and I think I will be going every three months after my next blood test.......I forget and need to look back at my notes.
Beth, 32
Major Flare Sept/Oct 07 ~ working on remission almost there
UC dx'd March 2000 (30 cenitmeters as of 2005-proctosigmoiditis)
Azathioprine 200mg 1xday nightly; Calcium and Vit D 500mg 3xday, Multi Vit, Folic Acid 400mg 2xday, Probiotics.
Minimal Change Disease (Kidney Disorder) Diagnosed Sept 2007
Prednisone 60/40mg alt days 1xday, Simvastatin 20mg 1xday, Diovan 160mg 2xday. Potassium 600mg 2xday, Fosomax 70mg 1xweek. MCD may be from hypersensitivty to 5ASA drugs.


Rio in Maryland
Veteran Member


Date Joined Nov 2007
Total Posts : 891
   Posted 1/25/2008 1:49 PM (GMT -6)   
I started on 100mg for 1 week and have been on 175mg since.  I've had weekly blood tests for the first month, then plan on once a month.  The GI specialist said that the dosage I'm on is based on guideline recommendations of 2.5 x body weight (in kilograms).
Rio, 31 yr old male - diagnosed with UC in 07/2006.
 
Alternative therapies for several months (SCD, ayurvedic treatment, VSL#3): didn't work and became anaemic. Canasa, 2 daily: remission for a month then flared-up.
07/07-11/07: 4800mg Asacol (6 x 400mg, twice a day) & Aloe Elite.
Completed first (6 week) tapered course of Pred in 10/07, flaring up since coming off it.
11/07: Switched from Asacol to 12 x 750mg Colazal (3 weeks on it and symptoms got worse)
12/07: Asacol 4800 mg, Started Azathioprene 175mg, Prednisone 60mg - taper.


Dansky
Veteran Member


Date Joined Mar 2005
Total Posts : 2844
   Posted 1/25/2008 2:13 PM (GMT -6)   
Numb78,

Weekly blood tests for the first 3 months is what I had when I started, I can't remember the dose I started on in 2006 but I'm now on 150mg a day, and it worked miracles for me after about 8 months, I consider it to be the wonder drug.

Take care.

Dave
Dansky Co-moderator UC forum
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CityWoman
Regular Member


Date Joined Jun 2004
Total Posts : 123
   Posted 1/26/2008 7:29 AM (GMT -6)   
I started last February at 50mg and had weekly test. After a couple months she moved me up to 100 mg and I continued with weekly tests. It's worthy to note that I was weaning off of prednisone at the same time I started Imuran for precisely the reason you site. I was told it took about 3 months to get into our system.
 
I moved from weekly, to bi-weekly, to monthly blood test. I am still on monthly.
 
I have no noticable side effects.
 
Judy

February 04: Rushed to hospital with severe blood haemorrhage. Diagnosed with indeterminate UC in 2/3 of my bowel. Treated with heavy doses of Pred; started Salofalk tabs and sups.

 

April 06: First major flare – more haemorrhaging. Colonoscopy once against confirmed indeterminate UC.

 

May 06: Started 40 mg Pred. Weaned down to 10mg by July 8, held at 10mg until December 20, tapering 1mg every 2 weeks, 5mg a day as of February 14. All this plus 10 Salofalk tabs daily.

 

Jan through May 2007: Suffering from severe headaches and vomiting likely caused by prednisone.

 

Feb 26 07: Started Imuran with continued success.

 

May 12 07: Final dose of prednisone after 50 weeks!


tjf
Veteran Member


Date Joined Dec 2005
Total Posts : 3238
   Posted 1/26/2008 7:53 AM (GMT -6)   
Here's my Imuran story. Started at 50mg and Prometheus test showed I wasn't at my therapeutic dose. Upped to 150mg. Prometheus showed way too high. Went down to 100mg. Prometheus said correct dosage. I have bloodwork every 3 months. It took from about April-Sept to really kick in for me. I'll be on it 2 years this April.
Tabitha (Tab)

100mg Azathioprine, 2 Fibercon, Colazal-9 a day, Acidopholis Pearls, Nexium

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Co-Moderator UC Forum


jujub
Forum Moderator


Date Joined Mar 2003
Total Posts : 10407
   Posted 1/26/2008 9:36 AM (GMT -6)   
I started at 50 for the first month, then up to 100. Promethius tests kept showing low levels, so I eventually went up to 200. I changed doctors and the first test he sent showed levels to high, so he dropped me back to 150, which got me in the therapeutic range. I had blood tests weekly for the first two months, then monthly for the next two, then every three months for the remaining time I was on Imuran.
Judy
 
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Asacol, Rowasa, Pentasa, Prednisone, Entocort, Azathioprine
Colazal,  Remicade, Nature's Way Primadophilus Reuteri.
In remission since April, 2006. Remicade has been my wonder drug.
 
Co-Moderator UC Forum

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