I had the worst flare of my life when I was six weeks pregnant. Stupidly I thought because I was in remission and have relatively minor UC that I would stay in remission. I didn't! I had to go on hydrocortisone enemas and I was sick as a dog for 14 days straight. All I did was go to the bathroom and lay on the couch. Literally. I had such bad cramps and bloody D/mucous I thought there was no way for me to keep my baby. Well she is now 20 months and healthy as anything. Such a delight! I wasn't on prednisone, so I can't speak to that, but I was on Rowasa and hydrocortisone enemas. Once I got mine under control I stayed in remission with only Rowasa enemas, which I slowly tapered all the way down to one a week until I stopped breastfeeding and flared again. I had to go on Asacol to get that one under control. The hormones really play a number on my UC, but once the initial shock of the hormone surge/change if I keep using my meds I can get things back under control. As for the meds effecting the baby I know exactly how you feel. Who wants to start their babies off with drugs in their system, however you have to remember the placenta is there for a reason to filter things for the baby and also these are category B drugs. You have to do what you feel is best, but honestly your body can not fight off UC and keep your baby without any drugs. My suggestion is do what it takes to get your flare back in remission and then try to taper as soon as you can, with the guidance of your GI. Good luck. I know this is a scary time, but you will get through it and then you will have nothing but joy(and sleepless nights!
Officially Diagnosed with UC in June 2003. Have had stomach issues since 1989. Unknown if they are related or not. Have mild/moderate UC. Have had 4 flares, the last one caused by hormones from stopping breastfeeding. Currently back in remission! Only taking 6 Asacol a day. Will take Rowasa enemas as needed. Colozal did not work for me. Luckily my UC is relatively minor and responds well to meds, but man do those flares hurt!