6MP dosing question

I have been taking 50mg of 6MP for six weeks now, and haven't seen much effect yet. However, my WBC decreased encouragingly from 8.8x10e3/uL to 5.9e3/uL in the first month, and the my 6-TGN level indicates I am in the correct therapeutic range. 

6-MP, like prednisone is very person to person when it comes to the level of effect per mg. For instance, the doc had to put my 6-MP up to 100mg per day to beat my immune system down to some useful level...

For me, I saw my WBC (white blood cell count) drop slowly over the space of 6 months before it stabilized off. For others, this happens very quickly.

No useful UC related effect kicked in till the 6 month mark for me, but others on this forum I have spoken to in other threads have had results as quickly as 3 weeks after starting on it (or Immuran - another immune suppression drug in the mercaptopurine family).

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"We are dreamers, shapers, singers and makers..." - Elric, elder Technomage

- 28yo male, Australia. Diagnosed at 16yo;
- 2xColazide, twice a day; 1x6-mp twice a day; 1xAbatacept 10mg/kg per month;
- 1xZinc per day, 1xDesert spoon of Metamucil smooth orange 3 times a day;
- 3xGarlic Oil caps 3 times a day, 7mL Olive Leaf Extract 2 times a day.

My WBC flunctuated wildly until it stablized eventually at the 6 month mark. I had to sometimes keep going in for weekly blood tests, then every month, then it would get all wacky again so I had to go back to weekly. Now that I've been on it for over a year, my WBC is stable and I go in for testing every 3 months.

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Thanks guys! That's interesting that your WBC fluctuated so much, Sherry. Could you tell it was doing that from how you good/bad felt or from your symptoms?

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Ben, 38

No I couldn't tell that my WBC was wacky. In fact, I was feeling pretty good with only minimal symptoms because at that time my body was still getting accustomed to the med and I was trying to get at my therapeutic level. But now that I'm at the right level, things have been going pretty good *knock on wood!*

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