Hi Chili - my husband too proved to be steroid dependant after being on it more than off it with a few unsuccessful tapers for a year 1/2. The imuran (azathioprine) is what finally got him off the prednisone. He has monthly blood tests to monitor 3 different things and then the doctor will prescribe another month's medication. So far the imuran has made a major difference for him.
The prednisone in all likelihood induced his osteopena and he is on Fosamax once a week for that. I was very nervous and scared about the imuran but the Dr reassured me it is a safe drug if he can tolerate it and it is monitored properly.
Obviously he would prefer not needing these meds but having him experience a terrible flare that kept him housebound for many months and to have some semblance of a life now it is a trade off.
The prednisone initially helped him until a year later WHAM he went into that awful flare that just took so long to get into some kind of control after the year 1/2 I mentioned above. I hated what the prednisone did to him. I pray it is never suggested to go back on it again as he is still in withdrawal from it and experiencing things that will take a while to clear up from what I have been told and read.
We are both now on a 2 week regimine to clear up H Pylori and man are these meds harsh. This is our 4th day and I don't like how I am tolerating them which is not well at all. My main fear and concern is that these meds do not make him regress in any way.
61 yr old male~Colitis 1st diagnosed Jan '05-cleared up within a few wks. Flared again in May '06 (now UC) & hospitalized 5/07-currently heading towards a remission. Osteopena of spine from prednisone DX 8/07 Oct 07 feeling quite normal most days. 150mg Imuran
Zero mg prednisone 12 Asacol, Lidocaine Hydrochloride Jelly 2%,multi vitamin, iron 1X day, DanActive, chewable calcium, fiber capsule 1x day, Prilosec 20mg, enalapril 10mg, glipizide 5 mg, zocor 40 mg, baby aspirin, (Fentanyl pain patch 50mg 72 hrs Morphine Sulf 15 mg twice daily)Cortifoam enema PM, Canasa suppositiry AM, folic acid 1mg, Fosamax 1x month