can azathioprine (imuran) affect the gall bladder?

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Beth75
Veteran Member


Date Joined Jul 2007
Total Posts : 2148
   Posted 2/10/2008 3:27 PM (GMT -6)   
I had an ultrasound done but no stones were found, GI gave me prilosec to take, it helps somewhat but I am still getting that pain after I eat.  I hope aza doesn't do anything, I am running out of options.
Beth, 32
Major Flare Sept/Oct 07 ~ no blood since Dec 07 ~ almost normal bm
UC dx'd March 2000 (30 cenitmeters as of 2005-proctosigmoiditis)
Azathioprine 200mg 1xday nightly; Calcium and Vit D 500mg 3xday, Multi Vit, Folic Acid 400mg 2xday, Probiotics.
Minimal Change Disease (Kidney Disorder) dx'd Sept 2007
Prednisone 40mg 1xday, Simvastatin 20mg 1xday, Diovan 160mg 2xday. Tekturna 150mg 1xday, Fursomide 20mg 1xday.  Potassium 100mg 2xday, Fosomax 70mg 1xweek. MCD may be from hypersensitivty to 5ASA drugs.


Red_34
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Date Joined Apr 2004
Total Posts : 23551
   Posted 2/11/2008 7:56 AM (GMT -6)   
Beth, where is the pain? I was reading about the side effects of Imuran and one of them said that you can get pain in the upper right side of your stomach........so I don't know if that would qualify as the gallbladder area?

http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682167.html#side-effects
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~Secondary Reynauds Syndrome -'04 - Norvasc~Fibromyalgia -'06~No meds
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MitzMN
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Date Joined Feb 2007
Total Posts : 640
   Posted 2/11/2008 8:07 AM (GMT -6)   
FWIW, Beth, I had my first gallbladder attack in June and had my gallbladder removed in October. I've been on Aza for six years, approximately.

No one suggested that they were related, but you never know, I suppose.

FWIW, I had two attacks, one quite mild, and one where I was in a cold sweat, in the middle of the night, passed out on the bathroom floor, in so much pain I was considering calling an ambulance -- and I'm not prone to do that kind of thing.

I wish you'd catch a break, darlin'. :-(

Mitz
Sporadic proctitis since about 1985. Mother had J-pouch surgery 1983.
DX'd with clostridium difficile in 2000. Pred, two courses of Flagyl, then Vancomycin finally got rid of it. 2001 colonoscopy dx'd left-sided UC. . Treated with prednisone, Rowasa, Asacol. Asacol not working, switched to Imuran. Three small flares since in 2002, 2005, and 2007, brought under control with steroid and Rowasa enemas. Lap Chole performed October 26, 2007, after gall bladder attack in June, '07.
Daily meds: 100 mg Azathioprine and 225 mg Effexor XR (for chronic, longstanding depression), many vitamins and Primadophilus Reuteri


Beth75
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Date Joined Jul 2007
Total Posts : 2148
   Posted 2/11/2008 9:38 AM (GMT -6)   
thanks for the info Red, i'll check w/my Doc when I see him in April, I think (hope) it's food related b/c it's only after I eat something or if I eat too much (darn pred!) and it is my upper right side right below my bra (easist way to describe).

Mitz sorry you had to go through that it sounds painful! Glad you are ok now.

yeah, I am pretty disheartened right now, the 5ASA's caused my kidney disease and now the pred I am on for the kidney disease is elevating my sugars and I could become type 2 diabetic (I am now on a no carb, no sugar, low salt diet). I am trying to stay positive but it's very hard, I guess it could be worse........at least my favorite beer is has very low carb, sugar and salt = )
Beth, 32
Major Flare Sept/Oct 07 ~ no blood since Dec 07 ~ almost normal bm
UC dx'd March 2000 (30 cenitmeters as of 2005-proctosigmoiditis)
Azathioprine 200mg 1xday nightly; Calcium and Vit D 500mg 3xday, Multi Vit, Folic Acid 400mg 2xday, Probiotics.
Minimal Change Disease (Kidney Disorder) dx'd Sept 2007
Prednisone 40mg 1xday, Simvastatin 20mg 1xday, Diovan 160mg 2xday. Tekturna 150mg 1xday, Fursomide 20mg 1xday.  Potassium 100mg 2xday, Fosomax 70mg 1xweek. MCD may be from hypersensitivty to 5ASA drugs.


suebear
Veteran Member


Date Joined Feb 2006
Total Posts : 5698
   Posted 2/11/2008 9:42 AM (GMT -6)   
Beth,

With the list of problems that have been caused by your UC meds, has your GI recommended surgery? I understand this is probably a step you do not want to take, none of us did, but you could regain your health, eat what you want, and not have to take all these meds. Life really is better post surgery!

Sue
dx proctitis in 1987
dx UC in 1991, was stable until 1998

1998 started prednisone, asacol, pentasa, nortriptylene, ativan, 6MP, rowasa enemas and suppositories, hydrocortisone enemas, tried the SCD diet, being a vegetarian, omega 3s, flax, pranic healing, yoga, acupuncture, probiotics

2000 lost all my B-12 stores and became anemic

2001 opted for j-pouch surgery- now living life med-free


Beth75
Veteran Member


Date Joined Jul 2007
Total Posts : 2148
   Posted 2/11/2008 9:57 AM (GMT -6)   
Sue, that thought has crossed my mind! I swear if I get one more stupid disease from drugs I may just do that.
Beth, 32
Major Flare Sept/Oct 07 ~ no blood since Dec 07 ~ almost normal bm
UC dx'd March 2000 (30 cenitmeters as of 2005-proctosigmoiditis)
Azathioprine 200mg 1xday nightly; Calcium and Vit D 500mg 3xday, Multi Vit, Folic Acid 400mg 2xday, Probiotics.
Minimal Change Disease (Kidney Disorder) dx'd Sept 2007
Prednisone 40mg 1xday, Simvastatin 20mg 1xday, Diovan 160mg 2xday. Tekturna 150mg 1xday, Fursomide 20mg 1xday.  Potassium 100mg 2xday, Fosomax 70mg 1xweek. MCD may be from hypersensitivty to 5ASA drugs.


MitzMN
Veteran Member


Date Joined Feb 2007
Total Posts : 640
   Posted 2/11/2008 5:59 PM (GMT -6)   
You are so young -- in the prime of you life!!! -- I just hate to see you having so many health struggles, Beth. Maybe it's time to explore the knife option -- at least explore it. How long have you been diagnosed? If you could stop all your meds, would your kidney disorder clear itself?

I just wish there was something I could do to help you. I get so discouraged reading what you're going through, honey.

Hugs,

Mitz
Sporadic proctitis since about 1985. Mother had J-pouch surgery 1983.
DX'd with clostridium difficile in 2000. Pred, two courses of Flagyl, then Vancomycin finally got rid of it. 2001 colonoscopy dx'd left-sided UC. . Treated with prednisone, Rowasa, Asacol. Asacol not working, switched to Imuran. Three small flares since in 2002, 2005, and 2007, brought under control with steroid and Rowasa enemas. Lap Chole performed October 26, 2007, after gall bladder attack in June, '07.
Daily meds: 100 mg Azathioprine and 225 mg Effexor XR (for chronic, longstanding depression), many vitamins and Primadophilus Reuteri

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