How many years on Imuran/6mp?

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tjf
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Date Joined Dec 2005
Total Posts : 3238
   Posted 2/10/2008 6:42 PM (GMT -6)   
Just curious as to how long you have been on either Imuran or 6mp. I've been on Imuran for almost 2 years.
Tabitha (Tab)

100mg Azathioprine, 2 Fibercon, Colazal-9 a day, Acidopholis Pearls, Nexium

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jujub
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Date Joined Mar 2003
Total Posts : 10407
   Posted 2/10/2008 7:40 PM (GMT -6)   
2 years this month on Remicade. I was never on 6MP, but I was on Azathioprine for about three years.
Judy
 
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Asacol, Rowasa, Pentasa, Prednisone, Entocort, Azathioprine
Colazal,  Remicade, Nature's Way Primadophilus Reuteri.
In remission since April, 2006. Remicade has been my wonder drug.
 
Co-Moderator UC Forum


MitzMN
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Date Joined Feb 2007
Total Posts : 623
   Posted 2/10/2008 8:10 PM (GMT -6)   
Around six years. (Sorry, I can't remember any better than that.)

So far, so good on the effectiveness side, and either none or not many side effects (maybe my chronic low energy is related) and no huge, scary problems like I read about as possibilities before I started this. Whew!

Mitz
Sporadic proctitis since about 1985. Mother had J-pouch surgery 1983.
DX'd with clostridium difficile in 2000. Pred, two courses of Flagyl, then Vancomycin finally got rid of it. 2001 colonoscopy dx'd left-sided UC. . Treated with prednisone, Rowasa, Asacol. Asacol not working, switched to Imuran. Three small flares since in 2002, 2005, and 2007, brought under control with steroid and Rowasa enemas. Lap Chole performed October 26, 2007, after gall bladder attack in June, '07.
Daily meds: 100 mg Azathioprine and 225 mg Effexor XR (for chronic, longstanding depression), many vitamins and Primadophilus Reuteri


Red_34
Forum Moderator


Date Joined Apr 2004
Total Posts : 23551
   Posted 2/11/2008 5:51 AM (GMT -6)   
6MP - 1 1/2 years for me :)
 @--->--SHERRY--<---@
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc -'92 - Colazal (9 daily), 6mp (50-100mgs), Prilosec, Biotin, Forvia, Pro-Bio**Unable to tolerate Asacol, Rowasa or Canasa** ~Allergies - Singulair
~Secondary Reynauds Syndrome -'04 - Norvasc~Fibromyalgia -'06~No meds
To help Healingwell - click here: DONATE
http://www.myspace.com/82595818
"The quality of my life depends on the quality of my thoughts."
 
 
 
 

 
 


chroniemomx2
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Date Joined Apr 2005
Total Posts : 2346
   Posted 2/11/2008 9:12 AM (GMT -6)   
Imuran...3 years. Had to stop in Nov. 2007 because of high toxicity.

Beth75
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Date Joined Jul 2007
Total Posts : 2148
   Posted 2/11/2008 12:35 PM (GMT -6)   
4 months on azathioprine..........not sure how much it is helping need to wait till I can taper off pred.
Beth, 32
Major Flare Sept/Oct 07 ~ no blood since Dec 07 ~ almost normal bm
UC dx'd March 2000 (30 cenitmeters as of 2005-proctosigmoiditis)
Azathioprine 200mg 1xday nightly; Calcium and Vit D 500mg 3xday, Multi Vit, Folic Acid 400mg 2xday, Probiotics.
Minimal Change Disease (Kidney Disorder) dx'd Sept 2007
Prednisone 40mg 1xday, Simvastatin 20mg 1xday, Diovan 160mg 2xday. Tekturna 150mg 1xday, Fursomide 20mg 1xday.  Potassium 100mg 2xday, Fosomax 70mg 1xweek. MCD may be from hypersensitivty to 5ASA drugs.


Mamas Boys
Veteran Member


Date Joined Oct 2005
Total Posts : 1460
   Posted 2/11/2008 1:38 PM (GMT -6)   
about 2 years for me.
KTM


WhiteSox1
Regular Member


Date Joined Oct 2007
Total Posts : 135
   Posted 2/11/2008 1:56 PM (GMT -6)   
I have only been on Imuran for about three months but I'm curious,  I read somewhere that long term use of Imuran can lead to tumors.  Does anybody know if this is true?
Pancolitis - Diagnosed on 9/6/07
Asacol 4 pills 3x's daily
Imuran 150mg.
Prednisone 10mg.
Canasa
Multi-Vitamins
Calcium with Vit. D Tablets


ks1905
Veteran Member


Date Joined Sep 2005
Total Posts : 5075
   Posted 2/11/2008 2:11 PM (GMT -6)   
The GI practice that I go to has had patients on 6-mp/imuran for 20+ years. I have been on it for 2.5 years.

--Keith
DX'd with Pan-Colitis June 2005
Current Status: Flaring since May
 
Current Meds:  50 mgs 6-mp, Colocort, Oral Cyclosporine (500 mgs)
Supplements:  None 
 


tjf
Veteran Member


Date Joined Dec 2005
Total Posts : 3238
   Posted 2/11/2008 4:11 PM (GMT -6)   
Thanks!

Keith....that is what I was curious about. I started taking it at 29.
Tabitha (Tab)

100mg Azathioprine, 2 Fibercon, Colazal-9 a day, Acidopholis Pearls, Nexium

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UCinNC
Veteran Member


Date Joined May 2007
Total Posts : 528
   Posted 2/11/2008 7:19 PM (GMT -6)   
i've heard long-term use of azathioprine is actually not too concerning. it has been in use since the 1980s, in much higher doses than we take it, so you figure some people have been on it almost 30 years by now..... I don't think the tumor risk is too great. that's my understanding.
30/Female/NC
Pancolitis dx 3/07
9 Colazal a day (was on 12 Asacol/day, but suddenly got sick from it)
150mg Imuran/day (steroid dependent, reached this dose 9/07)
Various vitamins, bit of fish oil, a probiotic.
Getting married October, 2008!!!!


Another UC wife
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Date Joined Jun 2007
Total Posts : 2111
   Posted 2/11/2008 7:36 PM (GMT -6)   
The Dr at Mayo clinic knew how concerned I was due to all the questions I had on my list that I was asking him on behalf of my husband regarding imuran (aza)

He told me not to be overly concerned. He said that it is a very safe drug if monitored properly(monthly blood tests are faxed to him before he has his secry fax a month's prescription to our pharmacy) and is tolerated within the limits by my husband. So far so good.

Once the year is over I don't know if the monitoring will be every 3 or every 6 months but he is watching real close this first year.

I recall his local GI mentioning something about a 5 year committment way back when...not sure what that is all about....

The Mayo Dr mentioned after the prednisone is eliminated (which it is) getting off all pain meds (maybe we are heading in that direction) and tapering the rectal meds which is already happening - he is not using the canasa on a regular daily basis and now using the cortifoam 3-4 times a week.

It will be interesting to see if the asacol gets decreased from 12 to whatever each day and ultimately does the imuran also get decreased?????

I know it has been said many times on this board about the mistake of getting off all meds but when a person is in a good remission do less meds keep you on a maintenance so that less medication is continually being processed by your body???

61 yr old male~Colitis 1st diagnosed Jan '05-cleared up within a few wks. Flared again in May '06 (now UC) & hospitalized 5/07-currently heading towards a remission. Osteopena of spine from prednisone DX 8/07  Oct 07 feeling quite normal most days.  150mg Imuran  Zero mg prednisone   12 Asacol, Lidocaine Hydrochloride Jelly 2%,multi vitamin, iron 1X day, DanActive, chewable calcium, fiber capsule 1x day, Prilosec 20mg, enalapril 10mg, glipizide 5 mg, zocor 40 mg, baby aspirin, (Fentanyl pain patch 50mg 72 hrs  Morphine Sulf 15 mg twice daily)Cortifoam enema PM, Canasa suppositiry AM, folic acid 1mg, Fosamax 1x month


dakotagirl
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Date Joined Apr 2006
Total Posts : 3402
   Posted 2/11/2008 7:44 PM (GMT -6)   
Getting close to 1.5 years here.

Keith - good to know your doc has long term results. A relief to know!
Pan-colitis and GERD diagnosed May 2003
 
Asacol 12 per day,  Azathioprine 75mg, Aciphex, Effexor XR, Forvia and a Probiotic
Osteopenia (hip and spine) from prednisone use.  Started Azathioprine because I was steroid dependent.
 
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ks1905
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Date Joined Sep 2005
Total Posts : 5075
   Posted 2/11/2008 8:41 PM (GMT -6)   
I think 6-mp has been around since either the 1950's or 1960's so there is lots of data on the med.

I think it is a good conversation to have with your GI.

--Keith
DX'd with Pan-Colitis June 2005
Current Status: Flaring since May
 
Current Meds:  50 mgs 6-mp, Colocort, Oral Cyclosporine (500 mgs)
Supplements:  None 
 


Another UC wife
Veteran Member


Date Joined Jun 2007
Total Posts : 2111
   Posted 2/11/2008 8:49 PM (GMT -6)   
I definitely have those questions in abeyance for the Dr but we are no where near that point in time. My basic questioning is to try to get an idea of others' experiences for comparison sake actually. I know everyone is different but just curious overall with personal experiences out there.

Can't get too anxious and ahead of ourselves - just some personal research and comparisons to put in the mix for the future.

61 yr old male~Colitis 1st diagnosed Jan '05-cleared up within a few wks. Flared again in May '06 (now UC) & hospitalized 5/07-currently heading towards a remission. Osteopena of spine from prednisone DX 8/07  Oct 07 feeling quite normal most days.  150mg Imuran  Zero mg prednisone   12 Asacol, Lidocaine Hydrochloride Jelly 2%,multi vitamin, iron 1X day, DanActive, chewable calcium, fiber capsule 1x day, Prilosec 20mg, enalapril 10mg, glipizide 5 mg, zocor 40 mg, baby aspirin, (Fentanyl pain patch 50mg 72 hrs  Morphine Sulf 15 mg twice daily)Cortifoam enema PM, Canasa suppositiry AM, folic acid 1mg, Fosamax 1x month


ks1905
Veteran Member


Date Joined Sep 2005
Total Posts : 5075
   Posted 2/11/2008 11:09 PM (GMT -6)   
I couldn't imagine being on 6-mp for 20+ years.... I suffer from fatigue and I blame a lot of it on the 6-mp; I'm sure some of it has to do with the UC too.

--Keith
DX'd with Pan-Colitis June 2005
Current Status: Flaring since May
 
Current Meds:  50 mgs 6-mp, Colocort, Oral Cyclosporine (500 mgs)
Supplements:  None 
 


CityWoman
Regular Member


Date Joined Jun 2004
Total Posts : 123
   Posted 2/12/2008 6:24 AM (GMT -6)   
Almost 1 year on Imuran.
Almost 4 years on Salafalk.
 
Judy

February 04: Rushed to hospital with severe blood haemorrhage. Diagnosed with indeterminate UC in 2/3 of my bowel. Treated with heavy doses of Pred; started Salofalk tabs and sups.

 

April 06: First major flare – more haemorrhaging. Colonoscopy once against confirmed indeterminate UC.

 

May 06: Started 40 mg Pred. Weaned down to 10mg by July 8, held at 10mg until December 20, tapering 1mg every 2 weeks, 5mg a day as of February 14. All this plus 10 Salofalk tabs daily.

 

Jan through May 2007: Suffering from severe headaches and vomiting likely caused by prednisone.

 

Feb 26 07: Started Imuran with continued success.

 

May 12 07: Final dose of prednisone after 50 weeks!


WhiteSox1
Regular Member


Date Joined Oct 2007
Total Posts : 135
   Posted 2/12/2008 8:04 AM (GMT -6)   
It's a relief to me to hear that everyone who has been on this medication for a long time has not had any serious side effects.  I was hestiant at first to take Imuran because of everything I have read about it.
Pancolitis - Diagnosed on 9/6/07
Asacol 4 pills 3x's daily
Imuran 150mg.
Prednisone 10mg.
Canasa
Multi-Vitamins
Calcium with Vit. D Tablets


MicheleV
Regular Member


Date Joined Sep 2004
Total Posts : 233
   Posted 2/12/2008 7:07 PM (GMT -6)   
3 1/2 years I believe.

I am in no rush to get off this drug as my only side effect is NO COLITIS. cool

I did years and years (pretty much my whole life) on other drugs that wouldnt keep me in remission and had the nastiest side effects for me.

I would do another 100 years of this drug.
Currently in remission since September 2004!!!  I am on Imuran 150 mg and am LOVING life!


julee70
Regular Member


Date Joined Oct 2007
Total Posts : 486
   Posted 2/13/2008 12:49 AM (GMT -6)   
Just passed my 2 year mark on 6MP. No complaints about it except that it doesn't keep me totally in remission all the time. Still, I've been way better on it. It took nearly 8 months to see the improvement. No side effects for me, though it took about a year to get my white blood count back up to normal.
-------
UC for the last ten years
Current Meds: 6MP
Past Meds: You name it; I've tried it.


Red_34
Forum Moderator


Date Joined Apr 2004
Total Posts : 23551
   Posted 2/13/2008 6:01 AM (GMT -6)   
Julee, I feel the same way about 6mp. I am way better on it but my only complaint is that is doesn't stop all the flares - just makes them more mild.
 @--->--SHERRY--<---@
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc -'92 - Colazal (9 daily), 6mp (50-100mgs), Prilosec, Biotin, Forvia, Pro-Bio**Unable to tolerate Asacol, Rowasa or Canasa** ~Allergies - Singulair
~Secondary Reynauds Syndrome -'04 - Norvasc~Fibromyalgia -'06~No meds
To help Healingwell - click here: DONATE
http://www.myspace.com/82595818
"The quality of my life depends on the quality of my thoughts."
 
 
 
 

 
 

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