H Pylori medication experiences

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Another UC wife
Veteran Member


Date Joined Jun 2007
Total Posts : 2111
   Posted 2/11/2008 7:18 PM (GMT -6)   
Hey there - anyone out here have any experience with taking the following:  flagyl, doxycycline and pepto bismol.  These are not the easiest meds to take - more so for me it seems.
 
Reason for asking...we are into day 5 of our 2 week regimine.  I have questions mainly for him.  For the past day 1/2 he has basically NO rectal discomfort.  He even had his annual urology appt and rectal exam this morning which sent him into a tailspin for 3-4 days last year and he's feeling ok which is a surprise.  His GI Dr mentioned something along the line that these meds may affect his current discomfort.  I am not complaining - this is a good thing (I think) and we are making sure we are taking the pepto bismol to help the stomach, extra acidophilus to replenish the bacteria etc.  Is this a short lived thing and after the 2 weeks things will return to what they were?  I am curious.
 
Now for me -- I am having a heck of a time tolerating these meds.  I am not having any of the serious warning reactions but these seem to be very harsh on me.  I feel like I have a furball in my throat and when I swallow it is like I have thick phlegm that won't go away.  Mild headaches, (definitely no alcohol for these 2 weeks + 3 days afterwards while on this medicine I already know about) coffee, tea, soda a bit of a burning sensation as well as some foods.  I have never had an ulcer but it almost feels like I have one now. A lot of rumbling, growling in the stomach and I feel hungry all the time.   General overall feeling of yuck.  I'm staying with it as I have to be rid of it and definitely don't want to mess things up as he is sticking with it.  I was 100% fine before this so this is way out of the norm for me.
 
We are both following the instructions - drinking full glasses of water, taking with food, not laying down for at least 1/2 hr when taking the doxycycline, we take the flagyl first and the doxy 2 hrs later and no other meds for at least 2 hrs after that.
 
Don't want to sound like a whimp I am just curious how others tolerated this and how it affected them.  I pray this eradicates it and when we are re-tested the end of March that it is G-O-N-E!!!

61 yr old male~Colitis 1st diagnosed Jan '05-cleared up within a few wks. Flared again in May '06 (now UC) & hospitalized 5/07-currently heading towards a remission. Osteopena of spine from prednisone DX 8/07  Oct 07 feeling quite normal most days.  150mg Imuran  Zero mg prednisone   12 Asacol, Lidocaine Hydrochloride Jelly 2%,multi vitamin, iron 1X day, DanActive, chewable calcium, fiber capsule 1x day, Prilosec 20mg, enalapril 10mg, glipizide 5 mg, zocor 40 mg, baby aspirin, (Fentanyl pain patch 50mg 72 hrs  Morphine Sulf 15 mg twice daily)Cortifoam enema PM, Canasa suppositiry AM, folic acid 1mg, Fosamax 1x month


Numb78
Regular Member


Date Joined Sep 2007
Total Posts : 63
   Posted 2/11/2008 7:48 PM (GMT -6)   
I had an awful experience myself with the H Pylori drugs. I'm pretty sure that it was the Flagyl that did me in but I was told by my GI to stop taking the meds after 3 days. I had severe tingling and burning in my arms and hands, my chest felt sunburnt, I couldn't sleep, had balance and muscle problems, I was vomiting after I ate anything, had the nasty metallic taste in my mouth... etc. Pretty well every nasty side effect possible. After I stopped taking the Flagyl it took about a week before I started feeling anywhere near normal again... Well normal for a flare up anyway!

Anyways, as I am battling a flare up at this time as well and just starting on imuran my doc decided to leave the h Pylori alone until my colitis is under control. There are other meds out there that can be used to fight the H Pylori so I think I'm going to try a different combination of drugs once my flare up is under control. The symptoms of the H Pylori are not bothering me nearly as much as my colitis flare so I'm willing to wait until the imuran kicks in before I try it again.
29 year old male, diagnosed after bad flare in Summer 2005, quickly brought into remission by pred and salofalk.   2 years symptom free after that!! 
Currently in a flare since summer 07 - I desperately miss remission!!!
Current Meds: 15mg Pred, 2000mg salofalk, calcium supplements, Pantoloc, Buscopan, Clonazopam
Started 100mg Imuran Jan 15/08 - no noticeable effect yet...


basa0806
Veteran Member


Date Joined Feb 2005
Total Posts : 2103
   Posted 2/11/2008 8:27 PM (GMT -6)   
I have had a horrible experience with h-pylori and the antibiotics. Before I was diagnosed with UC I had h-pylori. It was really bad at the time and they put me on flagyl. I started getting better and my prescription was at the end of the course so we asked my dr if I could stay on it for another couple days and he said it was fine, just pay attention because if you have sudden d it means that the antibiotic wiped out everything good. Well I got that sudden d and was sooo sick. So we went back in and it ended up the I had UC. To this day my mom swears that it was the antibiotic that brought me the UC (the same thing happened when I was a baby) I'm not sure why my dr didn't tell me to take a probiotic at the same time...?
As far as symptoms go, I remember having a nasty taste in my mouth all the time and they kind of made me nauseated. That's it though.
I guess if its really bothering you, talk to your doctor. The meds are supposed to make you feel better, not worse
Sam
Diagnosed March 2005
Remission since January/April 2006 (incident with mono)
3200mg Asacol, 25mg Amitriptlyine, Ortho Tri-cyclen lo, Imodium when I need it
"If you don't like something, change it. If you can't change it, change your attitude"
Maya Angelou


Another UC wife
Veteran Member


Date Joined Jun 2007
Total Posts : 2111
   Posted 2/11/2008 9:10 PM (GMT -6)   
Thanks for the info above. Maybe because the Imuran has taken hold and done a lot of good so far hubby seems to be tolerating this well. That was my main concern. We are making sure we take more acidophilus than usual to keep the pro biotic end of things in balance. So far no D for him and as I said he is feeling even better at least at the moment. I told him in the beginning to be very intuned if it even looks like he might be regressing and going towards a flare to immediately call the Dr.

Me..........well I'll give it a few more days before calling the Dr. I'm just aggravated as I didn't even know I had this and was feeling fine.

This H Pylori business was diagnosed from an endoscopy of my husband in July 05 and overlooked. We were not even aware one of us had it and subsequently passed it to the other. Who knows I could have had it first and gave it to him. Nevertheless we are now in the throes of having it treated.

I have read all the serious side effects and none of them are happening yet.

It just blows my mind to go from what I thought was healthy to this. Since it can be passed to one another. If he stays on it with no problem and these annoyances don't get any worse then I'll stick it out as I want to be rid of it too so I'm on the same course as he is. This seems to be the drug regimine most used to eradicate it and Lord knows I want this gone.

Once you eliminate this can you get this again????? We are due for a breath test the end of March and if it is negative which we hope do we have to worry about this in the future? (Would like to know where the heck we got it to begin with...lol)

61 yr old male~Colitis 1st diagnosed Jan '05-cleared up within a few wks. Flared again in May '06 (now UC) & hospitalized 5/07-currently heading towards a remission. Osteopena of spine from prednisone DX 8/07  Oct 07 feeling quite normal most days.  150mg Imuran  Zero mg prednisone   12 Asacol, Lidocaine Hydrochloride Jelly 2%,multi vitamin, iron 1X day, DanActive, chewable calcium, fiber capsule 1x day, Prilosec 20mg, enalapril 10mg, glipizide 5 mg, zocor 40 mg, baby aspirin, (Fentanyl pain patch 50mg 72 hrs  Morphine Sulf 15 mg twice daily)Cortifoam enema PM, Canasa suppositiry AM, folic acid 1mg, Fosamax 1x month


basa0806
Veteran Member


Date Joined Feb 2005
Total Posts : 2103
   Posted 2/11/2008 9:15 PM (GMT -6)   
Its passed from contaminated fecal matter. So its possible to get it again. A friend of my mom had it and he and his wife were told to get tests done regularly because its easy to get.
Sam
Diagnosed March 2005
Remission since January/April 2006 (incident with mono)
3200mg Asacol, 25mg Amitriptlyine, Ortho Tri-cyclen lo, Imodium when I need it
"If you don't like something, change it. If you can't change it, change your attitude"
Maya Angelou


love4cats
Regular Member


Date Joined May 2007
Total Posts : 458
   Posted 2/12/2008 7:29 AM (GMT -6)   
Another UC wife said...
Hey there - anyone out here have any experience with taking the following:  flagyl, doxycycline and pepto bismol.  These are not the easiest meds to take - more so for me it seems.
 
Reason for asking...we are into day 5 of our 2 week regimine.  I have questions mainly for him.  For the past day 1/2 he has basically NO rectal discomfort.  He even had his annual urology appt and rectal exam this morning which sent him into a tailspin for 3-4 days last year and he's feeling ok which is a surprise.  His GI Dr mentioned something along the line that these meds may affect his current discomfort.  I am not complaining - this is a good thing (I think) and we are making sure we are taking the pepto bismol to help the stomach, extra acidophilus to replenish the bacteria etc.  Is this a short lived thing and after the 2 weeks things will return to what they were?  I am curious.
 
Now for me -- I am having a heck of a time tolerating these meds.  I am not having any of the serious warning reactions but these seem to be very harsh on me.  I feel like I have a furball in my throat and when I swallow it is like I have thick phlegm that won't go away.  Mild headaches, (definitely no alcohol for these 2 weeks + 3 days afterwards while on this medicine I already know about) coffee, tea, soda a bit of a burning sensation as well as some foods.  I have never had an ulcer but it almost feels like I have one now. A lot of rumbling, growling in the stomach and I feel hungry all the time.   General overall feeling of yuck.  I'm staying with it as I have to be rid of it and definitely don't want to mess things up as he is sticking with it.  I was 100% fine before this so this is way out of the norm for me.
 
We are both following the instructions - drinking full glasses of water, taking with food, not laying down for at least 1/2 hr when taking the doxycycline, we take the flagyl first and the doxy 2 hrs later and no other meds for at least 2 hrs after that.
 
Don't want to sound like a whimp I am just curious how others tolerated this and how it affected them.  I pray this eradicates it and when we are re-tested the end of March that it is G-O-N-E!!!

I have recently finished taking a three week stint with Doxycycline for potential Lyme Disease infection.  I took it with food, full glass of water (actually took two glasses of water) cut out all milk products except yougurt and only then 2 hours before taking the antibiotics.  I also doubled up on my probiotics during this time.  I did have ill feelings when I was first on it, but they subsided in about a week.  Since I have stopped taking them about a month ago I have noticed a significant increase in gas but that is starting to get back to normal now.
 
 
Dx:  UC Proctitis 2006
 
Meds:  None so far. Garlic works to ease flares. My GI laughed when I told him and said it was just coincidence.
 
Diet:  Regular fresh garlic, Biobest yogurt daily, Omega 3 supplements, very limited junk food, carbs and processed food, low fat diet.  Lots of fresh fruit and veggies (limited potatoes). 
 
Added: tumeric and probiotics.
 
 


Another UC wife
Veteran Member


Date Joined Jun 2007
Total Posts : 2111
   Posted 2/12/2008 8:53 AM (GMT -6)   
Thank you love....we are taking a full glass at least of water along with some food - I assume the more water the better to help flush the kidneys - we also make sure 2hrs prior and 2 hrs after no dairy as that interferes with proper absorption of the medicine for the doxy.

The hardest part is the scheduling and fitting in the logistics of these 5 pills at 5 separate intervals in addition to his regular meds taken 3 times a day. Starting every day at 5am for meds is knocking the stuffing out of us!

Oh well just another week and 2 days to go!!!!!

61 yr old male~Colitis 1st diagnosed Jan '05-cleared up within a few wks. Flared again in May '06 (now UC) & hospitalized 5/07-currently heading towards a remission. Osteopena of spine from prednisone DX 8/07  Oct 07 feeling quite normal most days.  150mg Imuran  Zero mg prednisone   12 Asacol, Lidocaine Hydrochloride Jelly 2%,multi vitamin, iron 1X day, DanActive, chewable calcium, fiber capsule 1x day, Prilosec 20mg, enalapril 10mg, glipizide 5 mg, zocor 40 mg, baby aspirin, (Fentanyl pain patch 50mg 72 hrs  Morphine Sulf 15 mg twice daily)Cortifoam enema PM, Canasa suppositiry AM, folic acid 1mg, Fosamax 1x month

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