Rowasa-how quickly does it work?

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tooth fairy
Regular Member


Date Joined Jan 2008
Total Posts : 98
   Posted 2/12/2008 11:33 PM (GMT -6)   
Hi, everyone. I had a second colonoscopy last Thursday, which showed active disease only in my rectum and sigmoid colon. (Very much improved from the pancolitis scope taken in summer 2006!) As a result, my GI put me on rowasa enemas to control the rectal flare, and said to continue tapering my prednisone. I've only used two of the enemas, but both evenings I was unable to keep the medicine in for more than an hour. I am wondering if this is long enough to really have an effect on the diseased tissue. Also, how much time should I allow to see if the rowasa is effective? The first two doses don't seem to be having any effect on my frequency, though I have noticed less bleeding in the past 48 hours. I am just so tired of this flare, this is the 3d month with no real change in my symptoms. Garh! Thanks in advance to all your advice,
Erica, 31
Pancolitis, diagnosed July 2006, at age 29
Imuran, Asacol, Rowasa*(new!)
Still on prednisone (10 mg) taper, two more weeks
Experimenting with low residue diet, live culture yogurt and probiotics


quincy
Elite Member


Date Joined May 2003
Total Posts : 31006
   Posted 2/13/2008 2:35 AM (GMT -6)   
Hi...you should stay on it nightly until you are "normal" and off the pred at least...then you'll be tapering. Because you're on pred and tapering, your symptoms will yo-yo.

When I was first put on the Salofalk (same as Rowasa), my doc said that anything over half an hour is a huge plus....the goal is overnight. I was on it nightly for at least a few months.

You say evenings? or are you meaning bedtime when you're all snug as a bug laying on your left side.

Hang tough, your patience will pay off big time...try to ride it out for a while.

It's awesome, however, that your most recent c-scope has shown improvement. The rectum is really the most difficult and last area to heal....

Keep us posted,
quincy
*Heather*Status: mini flare Dec 28... tapered to every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals/supplements 
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....bromelain 1 - 2x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!


Red_34
Elite Member


Date Joined Apr 2004
Total Posts : 23551
   Posted 2/13/2008 7:48 AM (GMT -6)   
The longer you can retain the enema the better it will be. Sometimes if you warm the bottle a bit plus get the air out, it might help you retain it a bit better and for a longer period. But once the inflammation starts to settle, the longer you should be able to retain it.
 @--->--SHERRY--<---@
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc -'92 - Colazal (9 daily), 6mp (50-100mgs), Prilosec, Biotin, Forvia, Pro-Bio**Unable to tolerate Asacol, Rowasa or Canasa** ~Allergies - Singulair
~Secondary Reynauds Syndrome -'04 - Norvasc~Fibromyalgia -'06~No meds
To help Healingwell - click here: DONATE
http://www.myspace.com/82595818
"The quality of my life depends on the quality of my thoughts."
 
 
 
 

 
 


tooth fairy
Regular Member


Date Joined Jan 2008
Total Posts : 98
   Posted 2/14/2008 8:13 PM (GMT -6)   
Thanks for the tips! Tonight will be #4 with the rowasa, and things seem to be improving. (Yesterday was better than today, but today was better than Saturday kind of thing) I still haven't been able to keep the medicine in all night, but I have gotten a few hours in a row, so things seem to be looking up. At least now the bathroom trips seem to be directly related to my eating instead of all day long. Now I'm going about 30 minutes after each meal, and in the morning, but it's vastly improved from two weeks ago.

Your hints about warming the bottle helped tremendously, thanks!
Erica, 31
Pancolitis, diagnosed July 2006, at age 29
Imuran, Asacol, Rowasa*(new!)
Still on prednisone (10 mg) taper, two more weeks
Experimenting with low residue diet, live culture yogurt and probiotics


Mamas Boys
Veteran Member


Date Joined Oct 2005
Total Posts : 1460
   Posted 2/14/2008 11:53 PM (GMT -6)   
when I first started on Rowasa the doc told me to take 1/2 imodium 1/2 hour before and to only use 1/2 the bottle the first few times until I got used to holding it.  Then gradually increase to the whole bottle.  It really helped.  After the 2nd night I stopped the imodium and by the end of the week I was using the whole bottle.  Keep at it - any time in is better than none and eventually you get used to holding in that initial urge and just sleep through the night.  And yes - as others have said - warming the bottle first and expelling the air is a huge help.

KTM


jujub
Elite Member


Date Joined Mar 2003
Total Posts : 10407
   Posted 2/15/2008 12:32 AM (GMT -6)   
Awesome news from your scope! During the short time I was able to use the Rowasa, I found if I could lie really still in bed on my left side and retain it for an hour, I could usually hold it all night. KTM's suggestions sound good to me.
Judy
 
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Asacol, Rowasa, Pentasa, Prednisone, Entocort, Azathioprine
Colazal,  Remicade, Nature's Way Primadophilus Reuteri.
In remission since April, 2006. Remicade has been my wonder drug.
 
Co-Moderator UC Forum


quincy
Elite Member


Date Joined May 2003
Total Posts : 31006
   Posted 2/15/2008 1:21 AM (GMT -6)   
WooHoo....you'll soon be a pro!
q
*Heather*Status: mini flare Dec 28... tapered to every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals/supplements 
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....bromelain 1 - 2x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!


tooth fairy
Regular Member


Date Joined Jan 2008
Total Posts : 98
   Posted 2/16/2008 7:27 AM (GMT -6)   
You know, the one thing that drives me nuts about UC is the cycling-one day good, another day bad. It's so hard to pinpoint what, if anything, was the culprit for the bad day! (was it that bite of pear baby food? was it that stressful patient? was it the small coffee? am i just getting the flu?) Anyhow, for two nights I was able to retain the rowasa for a few hours-not all night, but 3+ hours, and both nights I did not sleep well; lots of cramping, rumbling, and once I did go to the bathroom to release the enema, I was back in there every hour after through the night. Daytimes weren't much better-lots of bathroom trips, some with cramping and mucous, others with actual BM. I'd estimate maybe 20 trips each day?
-So last night I was only able to hold the enema for about 6 minutes. After that though-I slept all night. And this morning (it's early yet though), just one BM with more form than usual, no bleeding. What gives? Do I need to just retain this enema for a short pass at first? Or could the enema be stimulating my digestive tract and making me feel worse, even while it's healing disease? I'll see how today goes and keep you all posted. Thanks again for everything-E
Erica, 31
Pancolitis, diagnosed July 2006, at age 29
Imuran, Asacol, Rowasa*(new!)
Still on prednisone (10 mg) taper, two more weeks
Experimenting with low residue diet, live culture yogurt and probiotics


quincy
Elite Member


Date Joined May 2003
Total Posts : 31006
   Posted 2/16/2008 3:19 PM (GMT -6)   
The enema will trigger the urge to have a bm...You might try doing a half an enema and see if you can hold it in all night and if you let it go, then you have another half to use.

You're improving....try not to micromanage everything. The healing process takes time. If you focus on the little stuff, you'll not see the progress.

The flu is respiratory, not gastro...

UC as it's healing goes up and down...you have a ways to go yet.

You're also tapering pred....so, really expect the ups and downs.

You might want to up some of the fibre with metamucil pills or even prodium to bulk up your stool.
Your colon needs to get more "exercise" rather than spasming. I would suggest you consider to ask the doc for some dicyclomine...which is an antispasmodic.

Hang tough...it can be a long ride sometimes. Just take it a day at a time and try not to let your frustration rule the process.

quincy
*Heather*Status: mini flare Dec 28... tapered to every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals/supplements 
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....bromelain 1 - 2x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!


tooth fairy
Regular Member


Date Joined Jan 2008
Total Posts : 98
   Posted 2/16/2008 10:19 PM (GMT -6)   
thanks, quincy. my husband said the same thing to me tonight over dinner about stepping back and watching the general trend instead of each hour's progress. I am normally ok about looking at the big picture, but I'm just so ready to be finished with this flare! at any rate, today continued to be a "good" day, and I'm a happy girl. Thanks again for everyone's help!
Erica, 31
Pancolitis, diagnosed July 2006, at age 29
Imuran, Asacol, Rowasa*(new!)
Still on prednisone (10 mg) taper, two more weeks
Experimenting with low residue diet, live culture yogurt and probiotics


quincy
Elite Member


Date Joined May 2003
Total Posts : 31006
   Posted 2/17/2008 3:44 AM (GMT -6)   
Good to hear you're doing the "happy dance"....it's a great feeling.

The only problem of feeling good one day and then not the next (regarding micromanaging)...we always make more of the bad. Continued disappointment is really counterproductive.

Do look at the big picture....you will gain patience which is realllly needed when on 5ASA meds. It's been a long time ago when I started using the enemas...but I will tell you it was a rough go at first. Ignorance is definitely bliss....no internet, not much info available about 5ASA meds...etc. My doc told me to be patient. By the second year, I had it figured out how to use them effectively to treat my flares earlier and earlier..taper process/scheduling, as I figured out, is solely dependent on my body symptoms.

When you "get it"...you'll be dancing a blue streak!!!

quincy
*Heather*Status: mini flare Dec 28... tapered to every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals/supplements 
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....bromelain 1 - 2x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!


princesscolon
Veteran Member


Date Joined Apr 2006
Total Posts : 733
   Posted 2/17/2008 1:06 PM (GMT -6)   
When I used to take the Rowasas, the 1st one or 2 times I couldnt hold it in, but then I was ok. I just had to lay on my left side, push the liquid in slowly, and then not move AT ALL. I would barley move to lift up my pjs and I had my hubby there to help me, and then he would throw the bottle away for me. I found that not moving at all helped me feel well enough to fall asleep and retain it all night.
Diagnosed with Left-sided Ulcerative Colitis 1995 at 15, Tried: Prednisone, Rowasa & Hydrocort. Enemas, Proctofoam, Sulfasalazine, Asacol, Probiotics, Fish Oil, Canasa, Enotcort, Colazol, Anamantle, etc... had almost recto-vaginal fistula in 2004, put on Remicade, August 2007:Increased Remicade dosage-700mg every 6 weeks,diagnosed w/ Psoriatic Arthritis & Fibromyalgia Current meds: Remicade 700mgs every 6 wks (had reaction, will start Humira Feb 11) Clorazepate, Proctofoam HC, Glucosamine 500, Vitamin B, Lomotil,  Tylenol pm, Lyrica for Fibromyalgia started 1/17/08

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