I was put on Colazal last August when I was first diagnosed w/uc (after 2 + years of symptoms and a clean colonoscopy the 1st time). Anyway, I had side effects with the Colazal after about
6 weeks and went off. My new doc put me on Lialda, and it didn't work. So, she put me on Asacol which didn't help. So, I took prednisone (30 mg, ugh) and 2 Lialda each day. Now, I'm off the prednisone (finally) and the Lialda is working- no bleeding or diarrhea or constipation. Hopefully, the Lialda will work for you, but it is the same med as Colazal and Asacol. You might need the boost of the prednisone, I'm sorry to say. Good luck, though!