Otherwise healthy individuals most often get this bug from taking antibiotics, which kill all the good germs in your gut, allowing the bad germs to proliferate and attack the lining of your colon.
Don't lay awake at night worrying about contracting this illness, be very careful about antibiotics, and it is unlikely you will ever have to deal with this illness.
That said, I do believe folks like us with colon issues are more susceptible than the average bear to getting c-diff.
Sporadic proctitis since about 1985. Mother had J-pouch surgery 1983.
DX'd with clostridium difficile in 2000. Pred, two courses of Flagyl, then Vancomycin finally got rid of it. 2001 colonoscopy dx'd left-sided UC. . Treated with prednisone, Rowasa, Asacol. Asacol not working, switched to Imuran. Three small flares since in 2002, 2005, and 2007, brought under control with steroid and Rowasa enemas. Lap Chole performed October 26, 2007, after gall bladder attack in June, '07.
Daily meds: 100 mg Azathioprine and 225 mg Effexor XR (for chronic, longstanding depression), many vitamins and Primadophilus Reuteri