After Prednisone

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New Member

Date Joined Nov 2007
Total Posts : 3
   Posted 2/21/2008 9:54 PM (GMT -6)   
Hi everyone, I was wandering if anyone a has had these same issues after prednisone.  I've been off prednisone since end of December and have been suffering from the following since...stiffness but not sure if it's joints or muscles (never had this before) mostly in the legs and shoulders, fatique, headaches (really bad ones at times), and a general all round blah feeling.
I'll be talking with my doc about this but in the mean time if anyone could shed some light this, it would be greatly appreciated

Diagnosed Sept/06 with UC
Currently on:
800mg Asacol
10mg prednisone
1 Salofalk/day

Veteran Member

Date Joined Aug 2007
Total Posts : 2204
   Posted 2/22/2008 10:45 AM (GMT -6)   
When you get off Prednisone, it takes time for your adrenal glands to adjust and start functioning normally again.

Check out this article:

Diagnosed with ulcerative colitis spring 1999.
Therapeutic dose sulfasalazine.
Probiotics, l-glutamine and fish oil caps. George's aloe vera juice and Mucosaheal. Oregano oil antibiotic, antiviral, antifungal.

Veteran Member

Date Joined Feb 2006
Total Posts : 5698
   Posted 2/22/2008 11:06 AM (GMT -6)   
This is normal. It took me a full year off pred to alleviate these symptoms.

dx proctitis in 1987
dx UC in 1991, was stable until 1998

1998 started prednisone, asacol, pentasa, nortriptylene, ativan, 6MP, rowasa enemas and suppositories, hydrocortisone enemas, tried the SCD diet, being a vegetarian, omega 3s, flax, pranic healing, yoga, acupuncture, probiotics

2000 lost all my B-12 stores and became anemic

2001 opted for j-pouch surgery- now living life med-free

Veteran Member

Date Joined Apr 2006
Total Posts : 3402
   Posted 2/22/2008 1:59 PM (GMT -6)   
Unfortunately, that's normal. The longer you were on pred, the longer it takes to go away.

How long were you on pred?
Pan-colitis and GERD diagnosed May 2003
Asacol 12 per day,  Azathioprine 75mg, Aciphex, Effexor XR, Forvia and a Probiotic
Osteopenia (hip and spine) from prednisone use.  Started Azathioprine because I was steroid dependent.
Co-Mod for the UC forum
Keep HealingWell running smoothly:

Regular Member

Date Joined Feb 2008
Total Posts : 55
   Posted 2/22/2008 5:42 PM (GMT -6)   
as far as i know, you should not take prednisone for more than a month.. because there are lots of side effects... I also had that feeling when i took prednisone for a month.. i also got some skin allergies...

New Member

Date Joined Nov 2007
Total Posts : 3
   Posted 2/22/2008 7:55 PM (GMT -6)   

ooohhh, thanks everyone for the input and the article on mayoclinic.  I thought it would only take a couple weeks to adjust.  I started prednisone in Aug at 20mg for a couple months then decreased 15mg in Oct, then 10mg in Nov and finished Dec on 5 mg.  So I guess after 5 months of prednisone it's going to take a while.

thanks again


Diagnosed Sept/06 with UC
Currently on:
800mg Asacol
10mg prednisone
1 Salofalk/day

Elite Member

Date Joined Mar 2003
Total Posts : 10407
   Posted 2/22/2008 8:04 PM (GMT -6)   
Prednisone is not recommended for long term therapy, but its use is not limited to a month. For some other diseases, or for some with UC who can't achieve remission with any other method, Pred is used longer-term. You have to weigh risks against benefits. In the short-term, the benefits of Pred outweigh the side effects. In the long run, they don't. That's why it's only used for long-term therapy in situations where there is no other option.
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Asacol, Rowasa, Pentasa, Prednisone, Entocort, Azathioprine
Colazal,  Remicade, Nature's Way Primadophilus Reuteri.
In remission since April, 2006. Remicade has been my wonder drug.
Co-Moderator UC Forum

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