inflamation markers?

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Veteran Member

Date Joined May 2007
Total Posts : 646
   Posted 2/23/2008 2:44 PM (GMT -6)   
So,  just switched doctors and had my first round of bloodwork with new doc.  She just called today with the results and said that I am anemic, low white blood count, but the one thing that concerned her were that my inflamation markers are sky high.  Now, I have been in a low-grade flare since May, but most of the time, things are pretty solid and there is minimal blood.  That said, what could sky-high inflamation markers mean?  I am getting nervous, especially since my last scope showed a really ugly precancerous poyp that was removed. 
She said she wants to scan no later than in the next couple of weeks. 

Diagnosed in April, 1998
Currently on (per day):
Pentasa 4 gms
Imuran - 150 mg 
Methylprednisolone - tapering down from 32 mg

Elite Member

Date Joined Mar 2003
Total Posts : 10407
   Posted 2/23/2008 3:32 PM (GMT -6)   
First of all, relax. Inflammation markers indicate just that, inflammation. Not cancer. So this has no meaning in that regard.

It could mean that your colon is in much worse shape than your symptoms suggest. It could mean you have an infection somewhere - in your colon or anywhere else. Follow up as the doctor suggested, but don't panic that this means cancer, because the lab findings just don't support that.

Let us know what you find out. I'll be keeping my fingers crossed that it's something easily and quickly resolved.
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Asacol, Rowasa, Pentasa, Prednisone, Entocort, Azathioprine
Colazal,  Remicade, Nature's Way Primadophilus Reuteri.
In remission since April, 2006. Remicade has been my wonder drug.
Co-Moderator UC Forum

Veteran Member

Date Joined Jul 2007
Total Posts : 714
   Posted 2/23/2008 3:44 PM (GMT -6)   
There are 3 main types of inflammation markers, C-R protein levels, Sedimentation count and platelet count. They count inflammation throughtout the body, not just in your colon.

Having low inflammation markers probably means your colon is in good shape. High inflammation markers don't necessarily mean that your colon is in bad shape but you should get it checked. Inflammation may be present in other areas of your body or there could be other processes affecting the accuracy of the readings. Anemia for instance will bias the inflammation markers reading as will an infection.

400-800 mg Asacol a day
Iron supplment,Probioitcs
Balanced Diet (...ish!!), Reduced Stress
"There are only about a half dozen things that make 80% of the difference in any area of our lives."

Veteran Member

Date Joined May 2007
Total Posts : 646
   Posted 2/23/2008 9:53 PM (GMT -6)   
Thanks so much for the replies.  I am certainly not new to this disease, but I must say, until recently I have never heard of inflamation markers!  I guess it's off to more research for me.  Thanks again!!

Diagnosed April 1998 - Pancolitis
Currently on (per day):
Pentasa 4 gms
Imuran 100 mgs

Veteran Member

Date Joined Sep 2005
Total Posts : 5132
   Posted 2/25/2008 11:10 PM (GMT -6)   

Your GI was probably referring to your Sedimentation rate A.K.A. Sed Rate or ESR. I wouldn't worry about it too much since you have UC and are flaring.... if you didn't have UC then it might be something to be concerned about.

If you had your Peroid when you had your blood drawn it may affect the results. Let your GI handle this and try not to worry about it.

P.S. Anemia will affect your sed rate too.

DX'd with Pan-Colitis June 2005
Current Status: Flaring since May 2007
Current Meds:  50 mgs 6-mp, Colocort, Oral Cyclosporine (250 mgs), Hyoscyamine .375 mgs
Supplements:  Forvia multi-vitamin

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