Posted 2/25/2008 11:15 PM (GMT -7)
I had the same reaction to remicade....I had to take 20 mg of prednisone the night before for pretreatment, then the benedryl prior and during my infussion. They also had to have the IV drip real slow or else I would start to become ill. Most people would be in and out in 1 1/2 to 2 hours it would take me 4 1/2 to 5 hours. I did this for a little over a year.

Humira was going to be the nest step but everything is in remission right now (I have crohn's) and I have been off all medications since September.

Crohn's and Ostomy in 2004

Posted 3/3/2008 12:34 PM (GMT -7)
I have been in a serious flare of UC (pancolitis) since Oct. 07. My GI doc put me on Humira (not any other biologic like Remicade) first. Started loading dose on Feb. 13, 08. Second dose just completed on Feb. 27, 08. Went from 10+ bms blood, etc. before first loading dose to 5-7 with no blood (3-4 of these are rapid fires in the morning until things are calmed down and cleared out). Very happy with results so far. My insurance covers Humira for UC even though its not FDA approved yet for UC. Study being completed April 08 that should allow Abbott, the pharmaceutical co, to get approval. My GI specifically did not want to try me on Remicade first because he was well aware of the mouse antibody issues. I have had no noticeable adverse events being on Humira so far. Make sure ahead of time that your insurance will cover the costs. You should also like the freedom of the self-administered shots.
Posted 3/3/2008 1:03 PM (GMT -7)
another note re. insurance coverage- my GI was telling me that managed care will cover Humira for UC if the patient is allergic to Remicade or Remicade fails the patient, ie- unable to induce remission. Go for it, I say!

diagnosed with UC '02
Asacol- 8 tabs/day
Remicade infusions
Imuran- 100mgs/day
Iron supplement

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