Prednisone and Cold Meds

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New Member

Date Joined Nov 2006
Total Posts : 12
   Posted 2/29/2008 7:06 PM (GMT -7)   
I am currently on 30 mg of prednisone per day. I have come down with a powerful cold. I know that prednisone interacts with some other medicines. Does anyone know if most cold medicines, such as nyquil or benadryln interact badly with pred. I know that alcohol isn't good with pred but the amount in a dose of nyquil shouldn't be that bad. I would like to get some sleep tonight but I'm not sure that will happen without the nyquil. Thanks for your help.

Regular Member

Date Joined May 2007
Total Posts : 167
   Posted 2/29/2008 9:37 PM (GMT -7)   
Funny, I just took a swig of Nyquil! I wouldn't worry too much about OTC cold medicines. I've asked my doc about several and he has never had any concerns about any. I've got a cough now and know I won't sleep without some Nyquil!
Dx Left-sided UC Dec. 2006
Azathioprine 200mg/day
Prednisone 7.5/5 (trying to taper-started at 60 6/1)
Lialda 2/day
Multivitamin, B complex vit., fish oil, calcium, fiber supplement, probiotic, adrenal support

Regular Member

Date Joined Feb 2007
Total Posts : 385
   Posted 2/29/2008 10:53 PM (GMT -7)   
i can't comment specificially on drug interactions because of liability issues but you may be able to run a drug interaction check on a medication website.
Pharmacy Student, Class of 2009.  Diagnosed 8/99.  Suffered for almost 10 years.  I am currently on the Specific Carbohydrate Diet and am nearing remission.  I feel fantastic!    I have lost so many years to this disease.  I decided to become a pharmacist to understand these drugs, and to help fellow sufferers of IBD.  My goal is to open up a pharmacy and take care of my patients(particularly explaining what the drugs do to you), compound special medications, and have a great practice. HAVE YOU CONSIDERED THE SCD DIET? IT HAS PUT ME IN REMISSION AND I PLAN ON GETTING OFF THE ASACOL SOON TOO!  (In remission since 2/15/08)
Meds 3200 mg Asacol, 2.5 mg Prednisone.  Doc wanted to put me on 6-mp or Remicade, but I refused to take the medications!  For me, diet works...

Forum Moderator

Date Joined Mar 2003
Total Posts : 10405
   Posted 3/1/2008 2:09 PM (GMT -7)   
Luke, the pharmacist where you get your prescriptions filled can probably also help you with this.
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Asacol, Rowasa, Pentasa, Prednisone, Entocort, Azathioprine
Colazal,  Remicade, Nature's Way Primadophilus Reuteri.
In remission since April, 2006. Remicade has been my wonder drug.
Co-Moderator UC Forum

Regular Member

Date Joined Jan 2008
Total Posts : 56
   Posted 3/1/2008 8:16 PM (GMT -7)   
Always took cold meds with pred without a problem. Just make sure there aren't NSAID's (anti-inflammatory) mixed in (so no advil, ibuprofen--only Tylenol/acetaminophen is okay).

23 yrs old
Diagnosed with UC: March 2004 with probable IBS component

Currently taking:
Asacol 4pills 3x/day
Prograf 5mg/day
(Prograf is my miracle drug! It doesn't seem to be well known, but it's fantastic!)

Previously Tried:
Prednisone (works, but such awful side effects!), 6-MP (gave me acute pancreatitis), Entocort, Cipro (antibiotic), Bentyl, Canasa suppositories, a couple different enemas

New Member

Date Joined Nov 2006
Total Posts : 12
   Posted 3/2/2008 7:02 PM (GMT -7)   
Thanks for the replies. I survived a couple days of cold meds without any problems and I think the cold is on its way out, but I'm not counting on it yet. 
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