Change in symptoms...pregnant...does it mean anything?

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Regular Member

Date Joined Dec 2005
Total Posts : 124
   Posted 3/2/2008 2:29 PM (GMT -6)   
Hi everyone.
I'm 18 weeks pregnant and started flaring in my 7th week of pregnancy.  Took Pentasa, Canasa which helped a little.  I switched to Lialda which I tried for a week however I was vomiting everything I ate that entire day (which included the morning pills I was taking)...I ended up losing a few pounds.  I got frustrated after 2 months of nausea/vomiting (despite taking Zofran) so I just stopped everything against the advice of my GI who wanted me to start Pred (I resisted).  So, the day after I stopped all my meds, the vomiting stopped, the bleeding stopped and I was extrememly happy.  The cessation of nausea and vomiting may well have been a coincidence...I know that.
Fastforward 2 weeks...we had a big scare with the pregnancy.  I had abnormal quad screen which gave me a 1 in 10 risk of Downs syndrome.  Had a detailed ultrasound which showed a few soft criteria for Down's (single umbilical artery and echogenic bowel).  These are non-specific but have been assoc with Down's.  That put my risk at 1 in 5.  I had an amniocentesis...everything just happened so fast...I really wasn't expecting this at all because i know the quad screen has a high false positive rate and I'm only 32.  Right after the amnio, for days I was an emotional disaster...miserable, anxious, depressed, crying name really never know what it's like until you go through it.  I was in such shock that although a I had 500,000 questions to ask the perinatologist, I couldn't even forumulate felt like a nightmare.  I know I should be stronger but I just couldn't control my emotions.  I was beside myself.
Okay...a few days ago I get the FISH results and MIRACULOULSY the results are negative for trisomy 21!  We are incredibly relieved and ecstatic but I also know that we are not out of the woods.  We are still waiting for the chromosomes to make sure there are no wierd translocations, etc...and we still have the single umibilical artery to deal with and we're hoping the echogenic bowel is gone on the next ultrasound.
Sorry for being so long with this...but the past week has been stressful with the baby scare and I do feel that my increase in symptoms are due to the recent stressful events (my colitis has always gotten worse with stress, despite medications).  In terms of my bowel habits, I've been having bms ranging from loose to diarrhea/mucous but no blood or very minimal.  This is certainly a change in my prior symptoms which were just formed bms with some blood/mucous.  I'm wondering if this could mean that the colitis is progressing? 
I know this sounds completely illogical, but after this whole scare and after I saw my little guy (it's a boy :) on the ultrasound I decided to stop all meds (I was also on Nexium) for fear of side effects and I think I'm's not D out of control (only 3-5/day).  What do you all think...could this be progression of the colitis?  With my daughter I flared during my 3rd trimester with bad bloody diarrhea (not diagnosed yet) and she turned out just perfect without meds....I'm hoping the same for this one...
Thank you so much for your insight

Elite Member

Date Joined Mar 2003
Total Posts : 10407
   Posted 3/2/2008 4:30 PM (GMT -6)   
I've never been pregnant with UC, but I know some of the folks here have said their UC changes during the pregnancy - for better or worse, or just different. If you're still off the 5-ASA's, that could be a factor also. Just remember that if you do start having bleeding or get yourself too run down, it can affect the baby as well.

Praying for a normal 46, xy for your lovely boy.
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Asacol, Rowasa, Pentasa, Prednisone, Entocort, Azathioprine
Colazal,  Remicade, Nature's Way Primadophilus Reuteri.
In remission since April, 2006. Remicade has been my wonder drug.
Co-Moderator UC Forum

New Member

Date Joined Feb 2008
Total Posts : 8
   Posted 3/2/2008 6:20 PM (GMT -6)   
I am new here and just learning what flares and remissions are. When I was pregnant with second child I was not taking meds, 1st trimester I had lots of problems. I was always vomiting and having flares. I started bleeding for a few days, went to see obgyn and he found tears in placenta. A blood test came back saying my son had spinabiffida, luckily it was wrong. My blood and baby's blood mixed, so it threw the test off. Went from 108lb to 160lb in months- more problems came from that. Needless to say, I blame UC for problems during pregnancy. I think it might be safer to take your meds. I'm not trying to scare you by saying any of that,please don't take it that way. I just think things would have been different if I did'nt have UC.
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