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New Member

Date Joined Mar 2008
Total Posts : 1
   Posted 3/2/2008 8:14 PM (GMT -6)   
Dr. wants to switch from asacol to pentasa.Can anyone give me any feed back about personal experience with pentasa.thanks

Elite Member

Date Joined Mar 2003
Total Posts : 10407
   Posted 3/2/2008 9:47 PM (GMT -6)   
It didn't do much for me. My current GI uses it for Crohns, but not for UC. He says it doesn't get to the areas where the med is needed the most because it dissolves to early in the GI tract.
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Asacol, Rowasa, Pentasa, Prednisone, Entocort, Azathioprine
Colazal,  Remicade, Nature's Way Primadophilus Reuteri.
In remission since April, 2006. Remicade has been my wonder drug.
Co-Moderator UC Forum

Veteran Member

Date Joined Mar 2006
Total Posts : 992
   Posted 3/3/2008 8:26 PM (GMT -6)   
Pentasa was absolutely garbage for me.. I took it for over 1.5 years, tried all kinds of doses and even the Canadian version (which is different than the American one in pill packaging). In fact, I think it actually HURT me-- it becomes a hundred little rock-hard medicine balls after the pill casing dissolves, and then those balls didn't seem to dissolve but came out whole.

You know how they tell UC'ers not to eat nuts or seeds b/c they tear up the colon wall? Well the geniuses behind Pentasa have designed a UC medicine that's as much like swallowing a bag of sharp seeds as humanly possible.

Boo to Pentasa. Two thumbs down. But you know very well that every UC'er is different, so give it a shot for a month...

Left-sided UC, Jun 2005. Flex-sig only... clear for first 20cms, then inflamed through next 30cms.


Pharmaceutical: Pentasa 3G/day, hydrocort 1x every 7 days
Probiotics: Acidophilus Pearls, Primadophilus Bifidus
Naturals: Caprylic Acid, Methylated B-12, Vit ACDE, Zinc (w/copper), Selenium, Turmeric, Bromelain, Luteolin
Killer Foods: Soda, Fried Food (especially french fries!), Beer, Red Wine, Pepperoncinis

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