Disco, I also started feeling better after the second infusion. My doc pre-medicates with Zyrtec, which doesn't make me sleepy, so I can have my infusion in the morning and then go to work if I want to. I am more tired, but my job is sedentary so it doesn't interfere. By the next day, I'm pretty much back to normal.
There are other drugs in testing or development, so Remicade isn't necessarily the end of the line.
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Asacol, Rowasa, Pentasa, Prednisone, Entocort, Azathioprine
Colazal, Remicade, Nature's Way Primadophilus Reuteri.
In remission since April, 2006. Remicade has been my wonder drug.
Co-Moderator UC Forum