A Good Probiotic please...

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UC spouse
Regular Member


Date Joined Feb 2008
Total Posts : 70
   Posted 3/3/2008 10:23 PM (GMT -6)   
I was looking for a good probiotic that's out there. Any suggestions? Is drink form better or capsule...or does it matter?

My husband's doctor gave him some samples of a probiotic called Align. Have any of you heard of this?

On another note, what are your thoughts about taking Immodium on a regular basis? I read somewhere that it said UC patients should never take Immodium, while we know a person who discovered that Immodium helped with reducing his frequencies.

Thanks for your advice!

pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20577
   Posted 3/3/2008 11:11 PM (GMT -6)   
I use primadophilus reuteri made by natures way with success, it has guaranteed intestinal release, only one/day is needed, aids with lactose intolerance, high cholesterol and for women, vaginal health (of course men can take it too)...only downside is it must be kept cold at all times, it's affordable and has helped me a great deal, it comes in caps or powder form.  Only contains a little potatoe starch for preservation, not like many that contain sugar, sugar alcohols, un-necessary dyes/coloring, additives, ect.

Better to use a fibre supplement (as my GI told me to daily for the rest of my life) rather than immodium.

:)


My bum is broken....there's a big crack down the middle of it!  LOL  :)


blessteve
Regular Member


Date Joined Jan 2008
Total Posts : 121
   Posted 3/3/2008 11:15 PM (GMT -6)   
The best, least expensive, the most, all natural and free.
I have previously posted this.



Info from this site http://users.chariot.net.au/~dna/kefirpage.html#morelinks

Free KEFIR grains are at this web sight. http://www.torontoadvisors.com/Kefir/kefir-list.php

Typical Microflora Isolated from Batches of Kefir Grains Divided into Four Genus Groups
LACTOBACILLI
Lactobacillus acidophilus
Lb. brevis
Lb. casei
Lb. casei subsp. rhamnosus
Lb. casei subsp. pseudoplantarum
Lb. paracasei subsp. paracasei
Lb. cellobiosus
Lb. delbrueckii subsp. bulgaricus
Lb. delbrueckii subsp. lactis
Lb. fructivorans
Lb. helveticus subsp. lactis
Lb. hilgardii
Lb. kefiri
Lb. kefiranofaciens subsp. kefirgranum subsp. nov *
Lb. kefirgranum sp. nov **
Lb. parakefir sp. nov **
Lb. lactis
Lb. plantarum
STREPTOCOCCI/LACTOCOCCI
Lactococcus lactis subsp. lactis
Lac. lactis subsp. lactis biovar diacetylactis
Lac. lactis subsp. cremoris
Streptococc lactis
Enterococcus durans
Leuconostoc cremoris
Leuc. mesenteroides


YEASTS
Candida kefyr [can utilize lactose]
C. rancens
C. tenuis
Debaryomyces hansenii *** [can utilize lactose]
Issatchenkia orientalis
Kluyveromyces lactis [can utilize lactose]
K. marxianus var. marxianus [can utilize lactose]
K. bulgaricus
K. fragilis / marxianus
Saccharomyces subsp. torulopsis holmii
Sacc. carlsbergensis
S. humaticus
Sacc. unisporus
Sacc. exiguus
Zygosaccharomyces rouxii ***
ACETOBACTER
Acetobacter aceti
A. rasens


Units Count of Microbes in Gram Stained Kefir Grains
Bacilli [single cells, pair, chains]
Streptococci [pair, chains]
Yeast [single cells]
The Means Range
Bacilli 66, 62-69%
Streptococci 16, 11- 12%
Yeast 18, 16- 20% [11]


Evolution Sequence among Genus Group of Organisms of Kefir during the Culture Cycle
Lactococci > Lactobacilli > Leuconostoc > Yeast > Acetobacter

Microbial Composition of Kefir at End of Fermentation [cfu/ml] ****
Lactococci : 1,000,000,000
Leuconostocs : 100,000,000
Lactobacilli : 5,000,000
Yeast : 1,000,000
Acetobacter : 100,000
Diagnosed panColitis 1990.
Current Meds Asacol x4 twice a day. X6 1/15/08
Pred for flares. I still have my colon THANK YOU GOD!!!
vitamins-veggie juice-wheat grass juice--fish oil
Started 1/01/08 PRObiotics
Freindly bacteria:raw milk-kefir made with raw milk--natto--probiotics
1/22/08 cultued veggies(probiotic)
Antifungus:Caprylicacid, Pau D Arco, Black walnut hull, Oregano oil
grape seed extract. 2/04/08 garlic
Anti inflammatory:fish oil  1/15/08 started Turmeric
1/10/08 Started healthy diet again.1/22/08 cultued veggies(probiotic)
 
 


lemonhead
Veteran Member


Date Joined Dec 2007
Total Posts : 1028
   Posted 3/4/2008 7:49 AM (GMT -6)   
I use Dr. Ohira's 12 plus. It is pretty good and very gentle. Also, I was told to never take immodium because if you use it a lot it will cause toxic megacolon. Please be careful.
diagnosed with left-sided UC in 1997.
Currently on 10mg Prednisone
12 caps of colazal
rowasa enema nightly
35 years old, white, female


Sarita
Veteran Member


Date Joined Mar 2005
Total Posts : 2486
   Posted 3/4/2008 8:18 AM (GMT -6)   
I would strongly encourage using a probiotic with strains of Bifidobacterium, especially B. infantis. This seems to be a pretty magical probiotic. Here's some research supporting it. If you want more info, I could find some for you, but these were just some of the articles I found. You can try doing a PubMed search for Bifidobacteria and you'll come up with tons of stuff, most of it Greek to the layperson, but these are good, peer-reviewed articles.

I take VSL#3 which has B. infantis and several strains of other probiotics. I am finding quite a profound effect on my symptoms.

***

Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active ulcerative colitis: a randomised controlled pilot trial.
Furrie E, Macfarlane S, Kennedy A, Cummings JH, Walsh SV, O'neil DA, Macfarlane GT.

BACKGROUND AND AIMS: Ulcerative colitis (UC) is an acute and chronic inflammatory disease of the large bowel with unknown aetiology. The immune response against normal commensal microorganisms is believed to drive inflammatory processes associated with UC. Therefore, modulation of bacterial communities on the gut mucosa, through the use of probiotics and prebiotics, may be used to modify the disease state. METHODS: A synbiotic was developed for use in UC patients combining a probiotic, Bifidobacterium longum, isolated from healthy rectal epithelium, and a prebiotic (Synergy 1), a preferential inulin-oligofructose growth substrate for the probiotic strain. Treatment was employed in a double blinded randomised controlled trial using 18 patients with active UC for a period of one month. Clinical status was scored and rectal biopsies were collected before and after treatment, and transcription levels of epithelium related immune markers were measured. RESULTS: Sigmoidoscopy scores (scale 0-6) were reduced in the test group (start 4.5 (1.4), end 3.1 (2.5)) compared with placebo (start 2.6 (2.1), end 3.2 (2.2)) (p=0.06). mRNA levels for human beta defensins 2, 3, and 4, which are strongly upregulated in active UC, were significantly reduced in the test group after treatment (p=0.016, 0.038, and 0.008, respectively). Tumour necrosis factor alpha and interleukin 1alpha, which are inflammatory cytokines that drive inflammation and induce defensin expression, were also significantly reduced after treatment (p=0.018 and 0.023, respectively). Biopsies in the test group had reduced inflammation and regeneration of epithelial tissue. CONCLUSIONS: Short term synbiotic treatment of active UC resulted in improvement of the full clinical appearance of chronic inflammation in patients receiving this therapy.

***

While they can make us feel better, modern antibiotics are notorious for stripping the body of helpful intestinal bacteria. Bifidobacteria supplementation can be especially important after taking a regime of antibiotics to restore a healthy balance of intestinal bacteria. Doctors say that up to 30 billion cfu per day may be necessary to "recolonize" the intestines.
Bifidobacteria are instrumental in preventing the growth of unfavorable organisms in the body like yeasts and sickness-causing bacteria. They are especially useful in the treatment and prevention of vaginal infections.(1) They may also help protect against gastrointestinal infections while enhancing overall immunity.(2)

Bifidobacteria may promote the healthy function of the digestive system and aid the body in absorbing many vitamins. They have potential for decreasing cancer risk by decomposing certain carcinogens. Bifidobacteria may also be able to remove excess cholesterol from the intestines before it is absorbed by the body.(3)

In addition to these overall health benefits of bifidobacteria, there are some targeted clinical applications. Studies suggest that bifidobacteria can, in some cases, relieve infant diarrhea.(4) Results of a study indicated that Bifidobacteria may alleviate symptoms of constipation.(5) Finally, bifidobacteria may ease gas and flatulence.(6)

Another study assessed the efficacy of bifidobacteria coadministered with a prebiotic and was also unable to demonstrate significant improvement in clinical outcomes.[17] Uncontrolled studies involving VSL#3 and S boulardii have yielded promising results, with induction of remission rates of 63% and 68%, respectively, in patients with active ulcerative colitis.[18,19] An international multicenter randomized controlled trial of VSL#3 for the treatment of acute active ulcerative colitis is currently under way, and results are expected in early 2007.
Co-moderator - IBS Forum


Sarita
Veteran Member


Date Joined Mar 2005
Total Posts : 2486
   Posted 3/4/2008 8:20 AM (GMT -6)   
Here's a link to some FAQs about VSL#3:

http://www.crohns.net/Miva/productinfo/whyVSL3.shtml
Co-moderator - IBS Forum


tjf
Veteran Member


Date Joined Dec 2005
Total Posts : 3238
   Posted 3/4/2008 8:33 AM (GMT -6)   
****Please use links instead of cutting and pasting lengthy research/info/etc. This is one of the forum rules.***
Tabitha (Tab)

100mg Azathioprine, 2 Fibercon, Colazal-9 a day, Acidopholis Pearls, Nexium

http://www.healingwell.com/donate
Co-Moderator UC Forum


princesa
Veteran Member


Date Joined Aug 2007
Total Posts : 2204
   Posted 3/4/2008 9:31 AM (GMT -6)   
I've had very good luck with Custom Probiotics' six strain powdered blend and all of Natren's formulas, although currently I'm only taking their Healthy Trinity capsules. If diarrhea is a problem or things are just moving abnormally quickly through the system, I understand the powders can be more effective.
Diagnosed with ulcerative colitis spring 1999.
 
Therapeutic dose sulfasalazine.
Probiotics, l-glutamine and fish oil caps. George's aloe vera juice and Mucosaheal. Oregano oil antibiotic, antiviral, antifungal.
 
 


dakotagirl
Veteran Member


Date Joined Apr 2006
Total Posts : 3402
   Posted 3/4/2008 10:13 AM (GMT -6)   
A couple more:

Culturelle - widely available at pharmacies - does not need to be kept cold
Pro-Bio - available online - does not need to be kept cold
Jarrow-dophilus - available online - does not need to be kept cold
Pan-colitis and GERD diagnosed May 2003
 
Asacol 12 per day,  Azathioprine 75mg, Aciphex, Effexor XR, Forvia and a Probiotic
Osteopenia (hip and spine) from prednisone use.  Started Azathioprine because I was steroid dependent.
 
Co-Mod for the UC forum
Keep HealingWell running smoothly:  www.healingwell.com/donate


Meesh
Veteran Member


Date Joined May 2006
Total Posts : 619
   Posted 3/6/2008 5:12 PM (GMT -6)   
I have had excellent results with Culturelle. I am finally succeeding in tapering off Prednisone. Within a few days of taking it I had a very "rumbly" day, but after my system got used to it I went from partial remission to full remission. My Remicade infusions had only been effective for four weeks, I am currently on a six week schedule, due for my next infusion this weekend and the last couple of weeks I have still been feeling fine.

It's been a godsend.

And yeah, steer clear of Immodium, Toxic Megacolon is even worse than it sounds if that's possible.

Meesh
Diagnosed UC April 27, 2006
Remicade infusions: 7/21/07; 8/18/07; 10/13/07; 12/15/97; 1/26/08
Lialda, 4 tabs in the morning; Protonix; Prednisone 4/27/06-present, starting yet another taper attempt, down to 15/10 mg alternating daily. Daily supplements: multivitamin w/folate; Culturelle; Fish oil capsules, calcium chews and/or Tums
12/1 - 12/29/07 weekly Venofer (iron) injections; 9 mg Entocourt EC; Xanax as needed; Lexipro 10 mg, Rowesa; Asacol; Colazal three 750 mg capsules 3X day; Bad reactions: Imuran (2/07)


uc_free
Veteran Member


Date Joined May 2007
Total Posts : 646
   Posted 3/6/2008 8:25 PM (GMT -6)   
Culturelle, by a MILE!!! I have tried so many probiotics - from the health food store's 30 dollars for a two week supply, to many over the counter types. Nothing has worked like this!!!

The last one I was on was actually part of a multivitamin. It was extremly expensive and was supposed to be the best around. Well, for me it exacerbated a flare.
Tara

Diagnosed April 1998 - Pancolitis
Currently on (per day):
Pentasa 4 gms
Imuran 100 mgs

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