Methotrexate Anyone?

Has anybody here tried a drug called Methotrexate.

I think its a immunosuppressent thats used after intolerance to imuran.

Is it effective, Is it worth a try?


G

Good morning, Gargamel. I don't know anyone who has used it for UC, but I do know it is used to treat certain cancers, rheumatoid arthritis, psoriasis and sometimes Crohn's. It works by suppressing the fast-growing cells in your body, i.e. skin cells, bone marrow, cancer cells. My experience with it was largely with cancer. I know it can also have some nasty side effects, which I'm sure you've already looked up.

Also, MTX is a very potent cause of serious birth defects if either parent is taking it when a pregnancy is conceived, so you have to use effective birth control while on it.

This link provides a little more information about MTX and other drugs we sometimes take:

http://www.gi.org/patients/gihealth/ibd.asp

I did a little searching and did find a study from the UK showing that it may be effective:

http://www.ncbi.nlm.nih.gov/pubmed/15709988

Hope this is helpful to you.

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I take it, but with Remicade to help prevent antibodies.
James

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Asacol 4 tabs 2x daily www.myspace.com/gardenerjames
Forvia once a day
Probiotic twice daily
Methotrexate 3 pills once a week
Actonel once a week
Calcium supp.
1 mg Folic Acid daily
Omega-3 once daily
12th Remicade infusion End of March