anyone on an immune suppresor but not a 5-ASA?

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Veteran Member

Date Joined May 2007
Total Posts : 528
   Posted 3/15/2008 3:57 PM (GMT -6)   
I am starting to think I can't tolerate 5-ASA drugs. But I have no problems with Imuran. am going to discuss this with my GI next week, but am thinking that maybe I should try just being on Imuran, and my beloved rectal meds, without any 5-ASAs. is anyone doing this? immune supressors but not the 5-ASAs? how is it going? is it ok to do this? I won't make any changes without the consent of my GI, but am just wondering..... thanks.
Pancolitis dx 3/07
9 Colazal a day (was on 12 Asacol/day, but suddenly got sick from it)
150mg Imuran/day (steroid dependent, reached this dose 9/07)
Cortfoam in AM, Rowasa in PM (is working wonders for me thus far)
Various vitamins, bit of fish oil, a probiotic.
Getting married October, 2008!!!!

Silent Lucidity
Veteran Member

Date Joined Nov 2007
Total Posts : 625
   Posted 3/15/2008 4:42 PM (GMT -6)   
I found that Azathioprine alone was enough.Did that twice for almost a year each time.Don't ask why I stopped;stupidity and the common,"I feel fine,don't need it anymore" patient attitude,that simple!

Definitely consult your GI first,but it sounds like a sensible course of action to me!
Procto-Sigmoiditis dx 1995.First Colonoscopy in ten years,on 29th Feb 2008,revealed moderate to severe Pancolitis.
Current meds;Pred,6 week tapered dose,starting at 40mg.Pentasa 2 x 500mg 4 x daily.
Got Ryche?

Regular Member

Date Joined Nov 2007
Total Posts : 124
   Posted 3/15/2008 5:54 PM (GMT -6)   
Yep, was taken off Pentasa early on and been on azathioprine for 3 months now. Couldn't seem to tolerate the Pentasa.
Diagnosed Indeterminate Colitis 25/11/2007 (update: told by consultant 15/01/08 in his opinion definitely UC). 1 x Solofalk Enema/day 40mg Prednisolone 35mg Prednisolone 30mg Prednisolone 20mg Prednisolone 25mg Prednisolone 20mg Prednisolone 15mg Prednisolone 4g Pentasa/day

Now on 150mg Azathioprine/Imuran, back up to 40mg Prednisolone, now tapered to 25mg Prednisolone, told to go back on Salofalk Mesalasine Enemas 2g 1 x night, Omeprazole 20mg, 2 x Calcium Adcal D3

Veteran Member

Date Joined Feb 2007
Total Posts : 648
   Posted 3/16/2008 8:33 AM (GMT -6)   
Can't tolerate some stuff. On Imuran alone. Works well for me!

Sporadic proctitis since about 1985. Mother had J-pouch surgery 1983.
DX'd with clostridium difficile in 2000. Pred, two courses of Flagyl, then Vancomycin finally got rid of it. 2001 colonoscopy dx'd left-sided UC. . Treated with prednisone, Rowasa, Asacol. Asacol not working, switched to Imuran. Three small flares since in 2002, 2005, and 2007, brought under control with steroid and Rowasa enemas. Lap Chole performed October 26, 2007, after gall bladder attack in June, '07.
Daily meds: 100 mg Azathioprine and 225 mg Effexor XR (for chronic, longstanding depression), many vitamins and Primadophilus Reuteri

Regular Member

Date Joined Oct 2006
Total Posts : 90
   Posted 3/16/2008 8:56 AM (GMT -6)   
I recently started 6mp and I asked my GI this same question, if eventually I would just take my 6mp dose and use that to keep me in remission. His reply was that the 6mp may be enough to hold me in remission, but he would want to continue taking one of the 5-ASAs if possible. The reason being was that supposedly regular use of 5-ASAs has been showed to reduce the risk of colon cancer while 6mp/Imuran alone does not. So, my understanding was that I would have to maintain my Colazal dose too. Now, I suppose if you can't tolerate the 5-ASAs then it defeats the purpose.
Diagnosed UC - 1993
32 year old female

Current Meds:
Prednisone - 40 Mgs
6-MP - 50 Mgs
Colazal (3 pills three times a day)
Probiotic, Folic Acid, Lysine

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