What was that about Folic Acid?

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:)
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Date Joined Feb 2008
Total Posts : 182
   Posted 3/18/2008 8:12 PM (GMT -6)   
I remember coming across something to the effect of 5-ASA's/Mesalamine can leach Folic Acid out of the body or inhibit absorbtion of it. Is this correct?
 
If this is true, does a Folic Acid supplement really help? Does it bypass the amount that gets leached out and manage to get in where it needs to go?
Dx: Dec. 2006 with UC
Thank G-d - Prednisone then 6MP, Rowasa and Asacol brought remission
Now Asacol 4tabs 2x a day.
Muiltivitamin, Iron and Folic Acid supplements


GardenerJames
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Date Joined Jan 2006
Total Posts : 616
   Posted 3/18/2008 8:32 PM (GMT -6)   
My GI has me taking 1 mg of folic acid per day. I guess it's supposed to help reduce the chance of colon cancer. He takes it too. It's cheap and you can get it over the counter.
James
Asacol 4 tabs 2x daily www.myspace.com/gardenerjames
Forvia once a day
Probiotic twice daily
Methotrexate 3 pills once a week
Actonel once a week
Calcium supp.
1 mg Folic Acid daily
Omega-3 once daily
12th Remicade infusion End of March


JewelsOK
Regular Member


Date Joined Jun 2007
Total Posts : 364
   Posted 3/18/2008 8:52 PM (GMT -6)   
Good question and I wonder about this myself. I know with sulfasalazine a person must take folic acid, but didn't think it was as important with other 5ASA's. My son's doctor rx'd folic acid, but my daughter's doctor says not until she is of child bearing age. I know of a child that took sulfasalazine and not folic acid and she suffered a stroke due to folic acid depletion.

Anyone out there know if all 5ASA's need folic acid supplementation?
Julie

Mom of Son 16 UC dx 07/02, Sulfasalazine, Imuran, folic acid, L. Reuteri, Zyrtec, Iron, Vit/Min

Daughter 9 UC dx 08/07 Colazal, 6MP, Iron, Vit/Min., Culturelle


Old Hat
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Date Joined Feb 2007
Total Posts : 5187
   Posted 3/18/2008 9:11 PM (GMT -6)   
I think the sulfa component of sulfasalazine is what makes folic acid supplement necessary. The other 5-ASAs do not contain any form of sulfa. Folic acid supplement is also advisable during major flares to support tissue repair. / Old Hat (nearly 30 yrs with left-sided UC ... [etc.])

Sara14
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Date Joined Mar 2007
Total Posts : 4509
   Posted 3/18/2008 11:00 PM (GMT -6)   
I think Old Hat is right. I will ask my new GI tomorrow if I remember. This has been something I've been wondering, too.
24 years old
Diagnosed with UC March 2007; yet to go into complete remission
Asacol 4 tablets 3x/day
Rowasa (generic) - nightly; Canasa (1,000 mg) in the morning
Nature's Way Primadophilus Reuteri 2/day; Chewable multivitamin; Metamucil; Viactiv


summerstorm
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Date Joined Aug 2006
Total Posts : 6571
   Posted 3/18/2008 11:16 PM (GMT -6)   
lots of different medicines can deplete your vitamin B levels, and also make it harder to absorbthose vitamins.  It never hurts to take folic acid or other b vitamins.  If you are a woman of child bearing age, you shoudl definetly be taking it, especially any woman with health problems, it can help reduce the risk of birth defects.  Also, taking B-12 can help with your energy level, as can the folic acid.  Anyway, you can't overdoes on it, unless you take a few bottles, so it won't hurt you or anything, and it is cheap

:)
Regular Member


Date Joined Feb 2008
Total Posts : 182
   Posted 3/19/2008 12:24 AM (GMT -6)   
thanks all for your knowledge and advice. Don't get me wrong, since I've read that article, I've been taking a Folic Acid supplement for oh, about a month or two. Even though my multivitamin has it.
summerstorm - i didn't know that about Vit. B-12, we have that at home, I'll look and ask further abt exactly what gets depleted and what needs replenishing in regard to the medications and their side effects.
Dx: Dec. 2006 with UC
Thank G-d - Prednisone then 6MP, Rowasa and Asacol brought remission
Now Asacol 4tabs 2x a day.
Muiltivitamin, Iron and Folic Acid supplements


Sara14
Veteran Member


Date Joined Mar 2007
Total Posts : 4509
   Posted 3/20/2008 12:50 PM (GMT -6)   
Hi again. I asked the GI at Mayo Clinic this question yesterday. He said people on sulphasalazine (sp?) do need to take folic acid, but those taking Asacol and other 5-ASA drugs do not need to, unless they are females trying to get pregnant.
24 years old
Diagnosed with UC March 2007; yet to go into complete remission
Asacol 4 tablets 3x/day
Rowasa (generic) - nightly; Canasa (1,000 mg) in the morning
Nature's Way Primadophilus Reuteri 2/day; Chewable multivitamin; Metamucil; Viactiv


quincy
Elite Member


Date Joined May 2003
Total Posts : 30829
   Posted 3/20/2008 3:11 PM (GMT -6)   
Take a multi B and you should be covered.

q
*Heather*Status: mini flare Dec 28... tapered to every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals/supplements 
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....zymactive 3 - 5x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!


:)
Regular Member


Date Joined Feb 2008
Total Posts : 182
   Posted 3/21/2008 1:32 AM (GMT -6)   
what does a B vitamin help with and specifically in relation to UC?


Dx: Dec. 2006 with UC
F, 23, NYC
Thank G-d - Prednisone then 6MP, Rowasa and Asacol brought remission
Now Asacol 4tabs 2x a day.
Muiltivitamin, Iron and Folic Acid supplements


julee70
Regular Member


Date Joined Oct 2007
Total Posts : 486
   Posted 3/21/2008 3:16 AM (GMT -6)   
Just to briefly add to the Folic Acid discussion -- Folic Acid is also good for people who take immunosupressors (like 6MP) because it helps promote overall blood health. For those of us getting our blood tested regularly to monitor white blood count, etc., Folic Acid is a good thing.

On the plus side for all of us-- the pills are really small! It's easy to add them to your daily pill regimen. (Not like trying to decide to take a monster omega-3 gel thingy. Ugh!)
-------
UC for the last ten years
Current Meds: 6MP since 2006, Cortifoam
Past Meds: You name it; I've tried it. (Asacol, Colazol, Pentasa, DiPentum, Rowasa, Canasa, Cortenema, sulfasalazine)

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