What are/were your symptoms after 6mp/Imuran had kicked in that you realized that it wasn't working right? I think I'm beginning to flare again because I woke up this morning with minor bleeding, solid bms - then mush x's 3, pain, cramping and urgency. It's the cramping and pain that makes me think that I'm flaring again. I have been on 6mp for 1 1/2 years but I still flare after going into short remissions. Usually my remissions only last a few months and that's it. I think I am going to call my GI on Monday and see if he wants me to start Colocort again or what.