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damo123
Veteran Member


Date Joined Jul 2007
Total Posts : 714
   Posted 3/23/2008 12:30 PM (GMT -6)   
I've had a lot of Heartburn and GERD issues for the last 2 weeks. I've tried all the usual solutions but was still feeling "off" without any nausea though.
 
By accident I missed my 4 Asacol tablets. The next day my GERD issues were gone, the stomach bloating was gone, my appetite was brilliant and I felt great. And to add to it the mucus in my BMs disappeared.
 
I'm wondering whether Asacol can cause stomach and GERD issues? Has anyone had a bad reaction to this med and it's related 5asa's with long term use?
 
D
 
Asacol and Iron as Needed. <I've fallen back into unhealthy ways and really enjoying it, burb!>
 
"Whatever you do in life don't berate yourself too much nor contragulate yourself too much. Your choices are half chance. So are everybody elses'"
 
 
 
 
 
 
 


Sherman Tank
Regular Member


Date Joined Jan 2008
Total Posts : 34
   Posted 3/23/2008 12:55 PM (GMT -6)   
I've never had a bad reaction to the asacol. In fact- Im never quite sure that the oral form is doing much of anything for me. Sorry not to be of more help.
Diagnosed proctosigmoiditis/ UC 2004
Misdiagnosed with just Hemeroids since I was 12!!
Bad flare after birth of first son in 2004,
another bad flare pregnant with 2nd baby summer 2006
recent reallly bad flare Dec 2007- 1st time w/ prednisone
Asacol for last 4 years 3pills 2X's, ROWASA as needed up to 3X's a day,
now just Asacol 3 pills-2X's a day, probiotics 2X's, fish oil, diet
Tryed-acupuncture, herbal remedies


quincy
Elite Member


Date Joined May 2003
Total Posts : 30591
   Posted 3/23/2008 1:05 PM (GMT -6)   
It says it's one of the side effects....although, I wonder how since it dissolves in the ileum and not in the stomach.

i've not had a problem with it for over 19 years.

Reflux is really a faulty sphincter at the esophagus/stomach...

Could it be food change or activity change you had/did yesterday...or what you didn't have yesterday?

q
*Heather*Status: mini flare Dec 28... tapered to every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals/supplements 
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....zymactive 3 - 5x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!


damo123
Veteran Member


Date Joined Jul 2007
Total Posts : 714
   Posted 3/23/2008 1:23 PM (GMT -6)   
I could well be blaming Asacol prematurely but I do remember people on here saying it gave them issues. It is a pretty mild med and I agree with the above comment that for me personally I don't think the oral form does anything for my UC.

I'm beginning to think that my stomach and heartburn problems which I assumed to be UC related are actually a form of GERD. I've read a bit about it this weekend and while its easy to suddenly to go OH I HAVE THAT CONDITION i do think i maybe a GERD-y.

Let's face it, I just have a terrible digestive system!
Asacol and Iron as Needed. <I've fallen back into unhealthy ways and really enjoying it, burb!>
 
"Whatever you do in life don't berate yourself too much nor contragulate yourself too much. Your choices are half chance. So are everybody elses'"
 
 
 
 
 
 
 


quincy
Elite Member


Date Joined May 2003
Total Posts : 30591
   Posted 3/23/2008 1:28 PM (GMT -6)   
One thing to keep in mind is that stomach issues can be a symptom of rectal inflammation for us UCers...slow simmering rectal inflammation. If you have the supps...why not start using them to see if it helps. Think of it as an experiment...lol...MY experiment on your butt..;-)

The asacol probably doesn't help on its own because it won't reach the rectum.
Don't cross it off your list too quickly, It has a job to do, but your expectations may be on a different level than what it's capable.
 
Oh...how many asacol in the past week have you actually missed since you're back to your unhealthy ways?

Trust me on this one...for at least a week.

quincy


*Heather*Status: mini flare Dec 28... tapered to every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals/supplements 
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....zymactive 3 - 5x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!


damo123
Veteran Member


Date Joined Jul 2007
Total Posts : 714
   Posted 3/23/2008 1:43 PM (GMT -6)   
Quincy,

No I agree. Rectal meds are far more effective for me than oral meds. I didn't believe that once but I endorse your view now. I always use them if BMs go astray.

I have to say that I pretty much gave up on my Asacol for a few months. Maybe 1 or 2 a day. I know!!! However during that time my BM were good and I felt fine. Not really worried to much bout my UC here. Thats ok. Its just that long term use of oral Asacol seems to cause me GERD issues and definitely affects my appetite. Nothing I cant handle. No nausea. But if oral Asacol really isnt doing anything for me I'd rather not take it. Quite happy to experiment with other 5asa's if need be,

Does anyone take maintance meds in purely rectal form?
Asacol and Iron as Needed. <I've fallen back into unhealthy ways and really enjoying it, burb!>
 
"Whatever you do in life don't berate yourself too much nor contragulate yourself too much. Your choices are half chance. So are everybody elses'"
 
 
 
 
 
 
 


Sara14
Veteran Member


Date Joined Mar 2007
Total Posts : 4201
   Posted 3/23/2008 2:25 PM (GMT -6)   
I think someone here has said that taking any type of pills on an empty stomach can cause gastritis. I'm not sure if that can cause GERD-like symptoms or not.
24 years old
Diagnosed with UC March 2007; yet to go into complete remission
Asacol 4 tablets 3x/day
Rowasa (generic) - nightly; Canasa (1,000 mg) in the morning
Nature's Way Primadophilus Reuteri 2/day; Chewable multivitamin; Metamucil; Viactiv


Mamas Boys
Veteran Member


Date Joined Oct 2005
Total Posts : 1460
   Posted 3/23/2008 7:50 PM (GMT -6)   
I know that my Colazal pills cause me some GERD issues.  When I was up to 12 pills a day due to a serious flare - the doc had me add in a Nexium because it was causing such burning in my throat.  Once I dropped back down to 9, the burning reduced to a more tolerable level.   But even now, in remission, I still have occassional burning from them - especially if I don't drink enough during the day.

KTM


Jsanders505
Regular Member


Date Joined Mar 2008
Total Posts : 94
   Posted 3/23/2008 10:50 PM (GMT -6)   
asacol and lialda increase bleeding for me personally

braillegirl
Regular Member


Date Joined Jan 2008
Total Posts : 66
   Posted 3/24/2008 6:06 AM (GMT -6)   
I had UC throughout my colon...altho it was mild to moderate. I now have in in the rectum and a small part of the sigmoid. I think the asacol is helping my upper colon. I have only taken 2 pills a day for the last 2 years. before that it was 4 pills a day. I am now up to 6 a day as I am in a severe flare...but getting better each day.
My thoughts is even if we don't think it is helping...It just might be. I no longer have active UC except in my lower colon.
jan
 DX: 1993: sulfasalazine; 1998: Pancolitis UC. asacal 2 2X daily, cortifoam,; 2003: Protitis UC severe flare. asaca 2 2X daily, canasa, cortifoam, cortenema
2008: Proctosigmoiditis severe flare. asacal 3 2X daily, canasa/discontinued while on pred, cortifoam/discontinued, Prednisone 40 mg to be tapered each week
Back on Prednisone 30 mg for 2 weeks then taper to 20 mg then we'll see. Back on Canasa at night.


Bum Deal
Regular Member


Date Joined Jan 2008
Total Posts : 34
   Posted 3/24/2008 6:08 AM (GMT -6)   

A few weeks back I asked one of my gastro docs if I could take 4 Asacol 3 times a day instead of 3 x 4, but when I took the 4 in one go I had bad D a couple of hours later. Didn't try again, and my other gastro doc (consistency? NHS? have they met?) said it was a big dose to be taking in one go.

I'm still trying to figure out myself if the Asacol is actually doing anything, and have wondered before if it might be adding to the problem. I'm a little scared to come off them to figure it out, though, as I seem to be fairly settled at the moment.


DW

Male 30 Years Old.

Diagnosed Pancolitis June 2007

Currently 20mg Prednisolone, 12 tablets Asacol, 50mg Imuran (started Dec 07), 25mg Mercaptopurine (following allergic reaction to Imuran)


GardenerJames
Veteran Member


Date Joined Jan 2006
Total Posts : 616
   Posted 3/24/2008 9:07 AM (GMT -6)   
Some people are actually quite "allergic" to asacol and can't take it at all. You might discuss this with your GI, because not taking it anymore might help you a lot. I had some improvement when I reduced my intake of it.
James
Asacol 4 tabs 2x daily www.myspace.com/gardenerjames
Forvia once a day
Probiotic twice daily
Methotrexate 3 pills once a week
Actonel once a week
Calcium supp.
1 mg Folic Acid daily
Omega-3 once daily
12th Remicade infusion End of March


princesa
Veteran Member


Date Joined Aug 2007
Total Posts : 2204
   Posted 3/24/2008 10:05 AM (GMT -6)   
I also improved when I asked to be switched from Asacol to the older drug, azulfadine.

Here are some articles on GERD you might find interesting:

http://articles.mercola.com/sites/articles/archive/2003/04/23/gerd-treatment.aspx

http://articles.mercola.com/sites/articles/archive/2002/10/12/gerd.aspx


Diagnosed with ulcerative colitis spring 1999.
 
Therapeutic dose sulfasalazine.
Probiotics, l-glutamine and fish oil caps. George's aloe vera juice and Mucosaheal. Oregano oil antibiotic, antiviral, antifungal.
 
 


yuckygut
Regular Member


Date Joined Feb 2008
Total Posts : 214
   Posted 3/24/2008 10:48 AM (GMT -6)   

My gerd was definately a problem in the past, not sure why I had to deal with both uc and gerd, but when I started drinking the Haldi drinks my gerd symptoms went away as well, I had previously stopped eating late into the evening as well.  I think the anti inflammatory aspect of the Haldi drinks helped to calm down my esophageal irritation as well.  At least I think that is what happened, I would try them to see if you get any benefit from them for your gerd as well as your uc.  And from what everyone is saying here on the site, I think being able to come off my colozal also helped in getting rid of my gerd. 

 

---------------------------------------------------

 

yuckygut

diangosed 1998

drink one Haldi daily

now off colozal and prednisone tongue


expecting226
Regular Member


Date Joined Jul 2007
Total Posts : 402
   Posted 3/26/2008 5:13 AM (GMT -6)   
Bum Deal - That is an interesting comment from your GI re: 4 Asacol at a time being a big dose. I have always taken my Asacol 4 pills, 3 times per day. That was the original direction from my GI in the beginning and has never changed.
Proud new mom of a beautiful baby boy!
Current Medications:
- Asacol (4 pills, 3x per day)
- Rowasa (1 enema daily, as needed)
- Folic Acid (1 mg, 1x per day)
- Calcium (600 mg, 2x per day)
- Prenatal Vitamin (1x per day)


quincy
Elite Member


Date Joined May 2003
Total Posts : 30591
   Posted 3/26/2008 12:03 PM (GMT -6)   
You can take 6 asacol twice daily....one more pill shouldn't have given you diarrhea...interesting.

There are days where I've forgotten my morning pills and take them all (6) at night..never any problems.
I guess I'm not sensitive to salicylates at all.
 
For reflux consider to take Zantac or other acid reducing meds...
q


*Heather*Status: mini flare Dec 28... tapered to every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals/supplements 
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....zymactive 3 - 5x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!


dakotagirl
Veteran Member


Date Joined Apr 2006
Total Posts : 3402
   Posted 3/26/2008 12:05 PM (GMT -6)   
I take mine 6 and 6 - and don't have issues when in remission. Interesting though.
Pan-colitis and GERD diagnosed May 2003
Osteopenia diagnosed Feb 2006
Status:  Flaring :(
 
Asacol 12 per day,  Azathioprine 75mg, Rowasa, Canasa, Aciphex, Forvia, and Pro-Bio
 
Co-Mod for the UC forum:  Keep HealingWell running smoothly:  www.healingwell.com/donate


Coalfire
Regular Member


Date Joined Jul 2007
Total Posts : 52
   Posted 3/26/2008 1:03 PM (GMT -6)   
Hi Damo,

Back to your question re rectal meds....I'm maintaining (of sorts) on asacol supps. They're the only thing that works, pred and oral asacol were a waste of time, same with predfoam/predsol enemas. My consultant suggested tapering down to one or two supps a week, which works for a while and then I just up it to nightly until I get a balance again. I get the telltale rectal rumbling (like stomach rumbling) at the start of a flare, so I just medicate accordingly 'til it settles. Hard to tell if my horrendous reflux was asacol or pred related as I stopped both simultaneously. I seem to be left with the legacy of occasional reflux, not helped by my white wine/peanut habit!
Current meds

Asacol Supps x 1 500mg nightly
Ferrous Sulphate 200mg x3 daily
Fish Oil 1000mg 1 cap
Acidophilus 2 tabs
Yakult


Diagnosed '96 ?colitis?crohns (biopsies inconclusive)
Remission for 11yrs, no meds
Current flare since April 07, Scope Sept. confirms ulc. proctitis


damo123
Veteran Member


Date Joined Jul 2007
Total Posts : 714
   Posted 3/26/2008 2:58 PM (GMT -6)   
I went off Asacol for a few days and my reflux was gone, my appetite was brilliant and my BMs werent that mucus-y. Then I went back on Asacol and all those symptoms have returned. I'd like to know for once and for all if I'm allergic to Asacol or its aspirin based formula so I'm just going off it for 2 weeks. I'm actually willing to put up with the risk of flaring just to know for once and for all if Asacol is causing some sort of intolerant reaction or if its doing anything for my UC.
Asacol and Iron as Needed. <I've fallen back into unhealthy ways and really enjoying it, burb!>
 
"Whatever you do in life don't berate yourself too much nor contragulate yourself too much. Your choices are half chance. So are everybody elses'"
 
 
 
 
 
 
 

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