Cytomegalovirus and UC

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New Member

Date Joined Mar 2008
Total Posts : 6
   Posted 3/24/2008 12:52 PM (GMT -6)   
Just got back from Mayo Clinic in Rochester last Friday.  Today, I get a call from my GI there.  Said I tested positive for Cytomegalovirus (CMV) in the CMV special stains made from my colon biopsies taken there.  I will also now be taking an antiviral drug to knock the CMV in my colon out.  The thinking is that this is at least a contributing factor why I have been unable to get this latest flare up of colitis under control at maximized therapy (prednisone 40-60 mg), Humira, canasa suppositories).
Has anyone had any experience being diagnosed with CMV in their colon?  Has anyone had any experience after antiviral therapy to share the results from this treatment and whether or not their UC went promptly back into remission after the 21 day antiviral treatment period?  Have also consulted with the surgical team there for 2 stage J-pouch surgery as a distinct possibility in the next 4-6 weeks after the Humira leaves my body.
37 year history of UC, left-sided, flaring since Oct. 07.  Prednisone (at 15 mg. now, Imuran 225 mg, Humira) 

Elite Member

Date Joined May 2003
Total Posts : 30993
   Posted 3/24/2008 3:23 PM (GMT -6)   
Hi...WOW, how awful for you, but good the doc did a test to find it.

It seems most people have been exposed, but since you're on immunosuppressants, it makes sense it took over.

I would say it's possible that's why you're experiencing problems getting into a remission...but once you have it, you'll always have it..right?

I hope you get on the mend soon....healing thoughts sent your way.
*Heather*Status: mini flare Dec 28... tapered to every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....zymactive 3 - 5x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!

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