It depends when you are at your worst. My doc has me taking mine at night because my reflux is worse overnight and first thing in the morning.
26 Year old married female. Diagnosed w/ CD 3 years ago, IBS for over 10 years before that, which was probably the CD. Currently on Pentasa 4 pills/4x day, hysociamine prn, nexium, and ortho evra. Good times!!!