Anyone Taking Dipentum?

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New Member

Date Joined Apr 2008
Total Posts : 2
   Posted 4/1/2008 9:39 PM (GMT -6)   
Hi--I'm new and a cursory glance through the forum doesn't show me anything about Dipentum. I'm currently going through a painful flare (blood and all) and turned to this site to see what's what.

I'm noticing most of you list your brief UC history so here goes:
UC diagnosed 13 years ago. Left side (aren't they ALL??), 250 mg Dipentum twice daily; Rowasa as needed with flares. I also take Omega 3 and Vit D with other meds for other ailments.


Regular Member

Date Joined Jun 2007
Total Posts : 89
   Posted 4/2/2008 11:59 AM (GMT -6)   

I was on the same dipentum dose as you for several months after trying asacol and colazol which didn't work.  It was the last resort before going on prednisone (Lialda wasn't out yet).  Luckily, I did well with dipentum until it eventually just stopped working too.  For some reason, my doctor put me on dipentum reluctantly, because he didn't feel it worked as well as the others--never explained why--I guess they all have their preferences.  2-250mg twice a day is the usual dose, though I often wonder if a higher dose would have worked better.  My doctor put me on Lialda then, and I've been on that ever since.   Dipentum is one of the older mesalamine medications and physicians nowadays usually put people on the newer asacol or colazol.  They are all basically all the same mesalamine drug, just different coatings, delivery systems and where, when and how they break down--so switching to different one sometimes helps.

Left sided UC almost 4 years
Current Meds: Lialda 3 in the morning, one at night
Winding down from flare that started in January
Alternating Cortenema and cortifoam at night--trying to wean off
Multi Vitamin/Mineral/Fish oil, Biotin, Extra Cal/Mag/D

Old Hat
Veteran Member

Date Joined Feb 2007
Total Posts : 5190
   Posted 4/2/2008 6:20 PM (GMT -6)   
Hello! I was prescribed Dipentum in the mid-1990s. It helped to reduce inflammation, but also prolonged loose bms so I never took it at the full recommended daily dose. Then when Colazal passed the NIH Phase 1 clinical trials ca. 2003, my gastro put me on it with the comment that it would take care of the D-problem that Dipentum perpetuated. And, thankfully, Colazal did work wonders for me! So I do think that Dipentum has gone out of style-- with Colazal or Lialda now the ticket. / Old Hat (nearly 30 yrs with left-sided UC; currently on 3 Colazal daily for maintenance of remission)

Old Hat
Veteran Member

Date Joined Feb 2007
Total Posts : 5190
   Posted 4/2/2008 6:26 PM (GMT -6)   
P.S. As I recall, the therapeutic daily dose of Dipentum in the 1990s was around 1 gram. So you seem to be taking about half as much daily-- 500 mg. / Old Hat
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