How soon should Remicade start working?

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Regular Member

Date Joined Mar 2008
Total Posts : 68
   Posted 4/10/2008 10:47 AM (GMT -6)   
I had my first Remicade infusion last Thursday and I am scheduled for my 2nd next Thursday.  My question is how soon should I start to feel the benefits of it?  Is one week too soon?  I was hoping this would be an immediate thing and I would go into remission.  One thing I have noticed is that my BM's arent watery they are just very loose.  Does this mean it is working and The frequency will stop soon?  I'm hoping for a miracle here!   Ha!

Eva Lou
Veteran Member

Date Joined Sep 2006
Total Posts : 3440
   Posted 4/10/2008 10:52 AM (GMT -6)   
For me, the results were nearly immediate. I know I slept thru that first night & was shocked. It really made me feel better right off- less urgency, less frequency, much less bm's & more solid. I believe most people do start to see noticeable results within 1 week- they say you really get the full therapeutic effect of Remicade after 4-6 infusions. Hope it works well for you!

diagnosed with UC '02
Asacol- 8 tabs/day
Remicade infusions
Imuran- 100mgs/day
surgery scheduled 5/7/08- perm ileo

Forum Moderator

Date Joined Mar 2003
Total Posts : 10407
   Posted 4/10/2008 2:05 PM (GMT -6)   
Some people notice a difference right away, others not until four or five infusions. For me, I was a little better after the second and a lot better after the third. Then for the whole first year, I just kept getting a little better all along until I stabilized where I am now. Give it some time, it isn't always immmediate.
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Asacol, Rowasa, Pentasa, Prednisone, Entocort, Azathioprine
Colazal,  Remicade, Nature's Way Primadophilus Reuteri. In remission since April, 2006.
Co-Moderator UC Forum
The information I share on this forum is based only on my own experience and study. It is important to consult your health care provider when making health-related decisions.

New Member

Date Joined Jan 2008
Total Posts : 9
   Posted 4/10/2008 2:39 PM (GMT -6)   
In my case, the results were almost immediate. After several months of moderate bleeding which was continuing even with 60 mg prednisone a day, the morning after my first infusion the bleeding simply stopped. Of course, this could also have been because the prednisone was finally working, or because of the natural cycle of UC, or because of psychosomatic placebo effects... Like all aspects of UC, there is a huge variation in symptoms, progression and efficacy of treatment amongst different people, so any prediction of how a medication is going to work for a particular individual is really fraught with uncertainty. Good luck with it, though!


Veteran Member

Date Joined Apr 2006
Total Posts : 733
   Posted 4/10/2008 2:43 PM (GMT -6)   
I saw a little improvement at first, then a big improvement at least 8 months after starting it. Try not to get discouraged, it sounds like it's working some already.
Diagnosed with Left-sided UC in 1995 at age 15, Prednisone, Rowasa & Hydrocort. Enemas, Proctofoam, Sulfasalazine, Asacol, Probiotics, Fish Oil, Aloe Juice, Canasa, Enotcort, Colazol, Anamantle, Remicade, etc... had 1 inch deep rectal ulcer 2004, put on Remicade, August 2007:Increased Remicade dosage-700mg every 6 weeks,diagnosed w/ Psoriatic Arthritis & Fibromyalgia Current meds: Clorazepate, Lomotil,  Tylenol pm, Lyrica started 1/17/08, Flagyl 750 mgs started 4/2/08, Humira started 4/4/08

Regular Member

Date Joined Apr 2008
Total Posts : 29
   Posted 4/10/2008 3:12 PM (GMT -6)   
I didn't start to feel better until after my second infusion. Even then it was a slow process. It took a long while to get back to normal, but you will eventually get there! It even sounds like its working quicker for you!

Regular Member

Date Joined Jan 2008
Total Posts : 154
   Posted 4/11/2008 9:52 AM (GMT -6)   
I'm supposed to start remicade in 2 weeks, but I currently feel fine buecause I'm on pred. How am I supposed to know if it's making any difference.

I am currently cycling off Pred, I'm down to 30 MG a day and and still have another 4 weeks before I'm off.
Diagnosed in spring 2005 at age 28
Currently on 12 asacol pills a day + Entocort
40 MG Pred cycle stating 3/26

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