Pred not working?

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Tinks Dad
New Member

Date Joined Apr 2008
Total Posts : 5
   Posted 4/11/2008 10:15 AM (GMT -6)   
My daughter has been on pred, 20 mg x2 daily to control a flare up for 4 weeks, (bleeding), no pains or other symtoms, 2-3 b/m's a day, blood on tissue and in bowl. stools semi-firm, not watery at all.
seems the pred has not stopped the bleeding?, any suggestions would be appreciated
She also just swtitched from Asacol to Liadal this past week, blood still present confused

Regular Member

Date Joined Apr 2008
Total Posts : 29
   Posted 4/11/2008 10:34 AM (GMT -6)   
I'm sorry to hear about your daughter. I'm a firm believer that Prednisone does more harm than good. I responsded better to steroid enemas. I would suggest that to your daughter if she is able to do them. There are basically no side effects because it does not get into the blood stream. 40mg is a lot to take for an extended period of time. I was on that amount for 2 months and it did not seem to help much.
21 Year Old College Student
Diagnosed UC December 2002
Remicade since December 2006
Colozal, Imuran, Prednisone

Regular Member

Date Joined Mar 2008
Total Posts : 113
   Posted 4/11/2008 10:49 AM (GMT -6)   
Is there a lot of blood or just a little? Is the blood bright red or darker? Does she have the urgency that's associated w/ a flare? I'm wondering if the UC could be doing better, but perhaps she has hemmorhoids that are causing the bleeding. (they can be internal, so aren't always visible to the eye). Just a thought. If she isn't having any other UC symptoms this would be my guess, but I'm no doctor!
Diagnosed w/ UC in August 2007
Current status: Flare

4 Lialda/day, Tapering off Prednisone (10mg), Rowasa at night, Wellbutrin XL

Tinks Dad
New Member

Date Joined Apr 2008
Total Posts : 5
   Posted 4/11/2008 11:11 AM (GMT -6)   
Thanks for the response, the blood is a bright red and is always at the tail end of the stool, she does not have any urgency associated with her b/m's, she is 9 yrs old, goes to school, swimming lessons, bike riding etc, never has an emrgency, we have scheduled an appointment for a 2nd opinion later this month

Regular Member

Date Joined Jan 2008
Total Posts : 154
   Posted 4/11/2008 12:35 PM (GMT -6)   
20MG might not be high enough, my doctor starts me and 40 or 60 than tapers down
Diagnosed in spring 2005 at age 28
Currently on 12 asacol pills a day + Entocort
40 MG Pred cycle stating 3/26

Regular Member

Date Joined Oct 2007
Total Posts : 348
   Posted 4/11/2008 12:49 PM (GMT -6)   
Any thoughts to trying cortenemas or rowasa? I know it's not appealing at all, but if they work, they work wonders.................
diagnosed with uc 27 years ago.  Enojoyed 10 - 12 year remission (approximately 10 of those years without any meds)
currently on Sulfasalazine 2 tabs 3x day. Folic acid, mesalamine enema every 4th night, will try to spread it out more. Omega 3, Probiotics, multi vitamin, cacium supplement, Biotin....
In remission since Jan 2008, can't believe it.............

Veteran Member

Date Joined Jul 2007
Total Posts : 2148
   Posted 4/11/2008 3:56 PM (GMT -6)   
Hi Tinks Dad,

I started Pred on 09/07 and actually got worse and flared on 09/21 (I had stopped Asacol cold turkey on 09/07) and what really helped me get my flare under control were hydrocortisone enemas. If she can take rowasa I would try those first.

Pred took a long time to help me and I was at 60mg a day.

I highly recommend asking GI about rectal meds!!!!
Beth, 32 ~ Major Flare Sept/Oct 07 ~ in remission
UC dx'd 03/00 (Proctosigmoiditis); Pancolitis since 09/07
Azathioprine 200mg 1xday nightly; Calcium and Vit D 500mg 3xday, Multi Vit, Folic Acid 400mg 2xday, Prilosec, Probiotics.
Minimal Change Disease (Kidney Disorder) dx'd 09/07 - partial remission since 03/08
Prednisone 20mg 1xday (taper 5mg a week from 60 = ), Simvastatin 20mg 1xday, Diovan 160mg 2xday. Enalpril 10mg 1xday, Fursomide 20mg 1xday, Fosomax 70mg 1xweek. MCD may be from hypersensitivty to 5ASA drugs.  Do you have edema? If so, check your protiens!
Pre-Diabetic from Prednisone use - Low carb/sugar diet & exercise.

Veteran Member

Date Joined Apr 2006
Total Posts : 3402
   Posted 4/11/2008 4:04 PM (GMT -6)   
Unfortunately, oral pred doesn't always work like we'd like it to. Have you mentioned the continuing symptoms to her doctor?
Pan-colitis and GERD diagnosed May 2003
Osteopenia diagnosed Feb 2006
Status:  Flaring :(
40mg pred, Asacol 12 per day,  Azathioprine 75mg, Cortifoam, Aciphex, Forvia, and Pro-Bio, Calcium, Vitamin D
Co-Mod for the UC forum:  Keep HealingWell running smoothly:

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