rectal steroids

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brian T1
New Member


Date Joined Mar 2008
Total Posts : 17
   Posted 4/11/2008 9:11 AM (GMT -7)   
I wasn't very impressed when my doctor put me on 20mg daily predfoam rather than 20mg oral pred. But a few days later and the rectal steroids seems to have worked 3 times faster than oral pred plus I haven't noticed any of the usual pred side effects yet.
 
Do other people find the same benefits with rectal steroids over oral steroids?
 
 
Dx mild pancolitis 2006
Mesalamine - Oral & Rectal
Vitamins & Supplements
 


Suesse
Regular Member


Date Joined May 2006
Total Posts : 45
   Posted 4/11/2008 9:23 AM (GMT -7)   
It depends whereabouts your UC is. Oral steroids will affect your entire body so if you can reach the inflamed area with foam or retention enemas then they are a much better option as you are far less likely to have nasty steroid side-effects.
I've used both foams and retention enemas and they worked well for me at the time.

brian T1
New Member


Date Joined Mar 2008
Total Posts : 17
   Posted 4/11/2008 9:30 AM (GMT -7)   
My inflammation was rectal and low left colon based. The rectal steroids seemed to have done the job in amazingly fast time.
Dx mild pancolitis 2006
Mesalamine - Oral & Rectal
Vitamins & Supplements
 


dakotagirl
Veteran Member


Date Joined Apr 2006
Total Posts : 3402
   Posted 4/11/2008 2:10 PM (GMT -7)   
Medication works best when applied directly to the site!
Pan-colitis and GERD diagnosed May 2003
Osteopenia diagnosed Feb 2006
Status:  Flaring :(
 
40mg pred, Asacol 12 per day,  Azathioprine 75mg, Cortifoam, Aciphex, Forvia, and Pro-Bio, Calcium, Vitamin D
 
Co-Mod for the UC forum:  Keep HealingWell running smoothly:  www.healingwell.com/donate


quincy
Elite Member


Date Joined May 2003
Total Posts : 30082
   Posted 4/12/2008 12:21 AM (GMT -7)   
Good to hear Brian. Are you still on Asacol? How many?

You would be best to NOT WANT pred..LOL!

What did the doc prescribe regarding schedule of them?

q
*Heather*Status: mini flare Dec 28... tapered to every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals/supplements 
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....zymactive 3 - 5x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!


brian T1
New Member


Date Joined Mar 2008
Total Posts : 17
   Posted 4/12/2008 8:18 AM (GMT -7)   
For the time being my doctor said to remain on 6 a day and when the flare is over he'll assess the Asacol again.

As for prefoam he had me at 40mg for 3 days, down to 20mg for next 3 days and if things remain good then a week of 20mg every second day. This seems a bit fast, perhaps?

I'd like to explore foam-based maintenance drugs? Do they exist outside of Asacol suppositories in the UK?
Dx mild pancolitis 2006
Mesalamine - Oral & Rectal
Vitamins & Supplements
 


Beth75
Veteran Member


Date Joined Jul 2007
Total Posts : 2148
   Posted 4/12/2008 12:20 PM (GMT -7)   
the hydrocortisone enemas really helped jumpstart my last flare into remission, the pred took a long time for me a couple of months.

Beth, 32 ~ Major Flare Sept/Oct 07 ~ in remission
UC dx'd 03/00 (Proctosigmoiditis); Pancolitis since 09/07
Azathioprine 200mg 1xday nightly; Calcium and Vit D 500mg 3xday, Multi Vit, Folic Acid 400mg 2xday, Prilosec, Probiotics.
Minimal Change Disease (Kidney Disorder) dx'd 09/07 - partial remission since 03/08
Prednisone 20mg 1xday (taper 5mg a week from 60 = ), Simvastatin 20mg 1xday, Diovan 160mg 2xday. Enalpril 10mg 1xday, Fursomide 20mg 1xday, Fosomax 70mg 1xweek. MCD may be from hypersensitivty to 5ASA drugs.  Do you have edema? If so, check your protiens!
Pre-Diabetic from Prednisone use - Low carb/sugar diet & exercise.


quincy
Elite Member


Date Joined May 2003
Total Posts : 30082
   Posted 4/12/2008 12:42 PM (GMT -7)   
Brian...sounds like a good plan. You should, however, continue the decrease/taper to 3 days, 4 days..etc. and stay on the foam once a week at least.

You should also stay on the Asacol....6 a day is maintenance...forever. Really.

Again, your goal should NOT be to use pred. I personally think it sets up a person to hurry a flare treatment and neglect the importance of maintenance and early treatment with rectal meds.

Tell me why again you aren't using the 5ASA rectal meds and what happened when you were on them? Were you tapering to maintenance..etc?

quincy
*Heather*Status: mini flare Dec 28... tapered to every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals/supplements 
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....zymactive 3 - 5x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!

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