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mikeg999
Regular Member


Date Joined Apr 2008
Total Posts : 62
   Posted 4/13/2008 7:08 AM (GMT -6)   
Morose topic but prompted by a question from my wife. I have left side uc since age 49 and was in remission via colazyl from 2003 to 2007. I have been in a severe flare since November am being encouraged to go for Remicade or Humira.

Other than uc, I consider myself exceptionally healthy (except for being on pred-20/day and for the last week 40/day). Is there any data or insights about what remi or humira may do to ones lifespan?

Thanks
54 yo male
First flare at age 49


damo123
Veteran Member


Date Joined Jul 2007
Total Posts : 714
   Posted 4/13/2008 7:54 AM (GMT -6)   
Hi,

I work as a statistican myself so I've done a bit of research on this.

The reduction in longevity due to having UC is very small - a few months. So for the average person having UC only slightly reduces your lifespan.

The new drugs like Imuran and Remi etc have not been on the market long enough to analyse accurately their effect on longevity. If anyone tells you otherwise it's simply wrong.

However the FDA will do extensive research and projections on all drugs and make assumptions about how they think the drug will effect your mortality. It would be very rare for them to give apporval to a drug that they thought would reduce lifepsan by more than 12 months. Of course the assumptions that they make could be wrong.
Asacol and Iron as Needed. <I've fallen back into unhealthy ways and really enjoying it, burb!>
 
"Whatever you do in life don't berate yourself too much nor contragulate yourself too much. Your choices are half chance. So are everybody elses'"
 
 
 
 
 
 
 


mikeg999
Regular Member


Date Joined Apr 2008
Total Posts : 62
   Posted 4/13/2008 8:19 AM (GMT -6)   
Thanks for your thoughtful repy
54 yo male
First flare at age 49


quincy
Elite Member


Date Joined May 2003
Total Posts : 30384
   Posted 4/13/2008 11:09 AM (GMT -6)   
Mike...have you tried any rectal meds?

Maybe something to consider before the big-guns.

Regarding life-span....some of us do get UC-related liver disease which is fatal, but not terminal (interesting perspective). A liver transplant buys time when the patient's liver cannot sustain life..., but interestingly, the new liver will also get the UC-related disease eventually....so, I would think that cuts down on life-span if it's active.

I believe the goal to keep everything nice and quiet helps.

quincy
*Heather*Status: mini flare Dec 28... tapered to every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals/supplements 
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....zymactive 3 - 5x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!


mikeg999
Regular Member


Date Joined Apr 2008
Total Posts : 62
   Posted 4/13/2008 5:49 PM (GMT -6)   
I have been following your docs advice-Rowasa (can't hold it), Canasa, Cortifoam and for the last 10 day hydrocortisone enemas combined with 40mg oral pred. Seems a little better the last 2 days.
54 yo male
First flare at age 49

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