Just put on Imuran...

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Regular Member

Date Joined Jan 2008
Total Posts : 27
   Posted 4/16/2008 1:01 PM (GMT -6)   
Hey ya'll. My doc just put me on Imuran, what are your experiences with Imuran? Did it help?? I did a search but couldn't find much on it. Thanks.
Chris 21/M
Diagnosed Sept. 07
Salofalk 500mg
Status: 3-5 BMs a day. Each one semi-loose and each one urgent!

Veteran Member

Date Joined Jul 2007
Total Posts : 2148
   Posted 4/16/2008 1:31 PM (GMT -6)   
I have been on it since Nov 07 and I think it's helping me, wont know for sure till I am completey off the pred. I take it at night b/c it made me groggy during the day. Other than that no issues.
Beth, 32 ~ Major Flare Sept/Oct 07 ~ in remission
UC dx'd 03/00 (Proctosigmoiditis); Pancolitis since 09/07
Azathioprine 200mg 1xday nightly; Calcium and Vit D 500mg 3xday, Multi Vit, Folic Acid 400mg 2xday, Prilosec, Probiotics.
Minimal Change Disease (Kidney Disorder) dx'd 09/07 - partial remission since 03/08
Prednisone 20mg 1xday (taper 5mg a week from 60 = ), Simvastatin 20mg 1xday, Diovan 160mg 2xday. Enalpril 10mg 1xday, Fursomide 20mg 1xday, Fosomax 70mg 1xweek. MCD may be from hypersensitivty to 5ASA drugs.  Do you have edema? If so, check your protiens!
Pre-Diabetic from Prednisone use - Low carb/sugar diet & exercise.

New Member

Date Joined Jan 2008
Total Posts : 11
   Posted 4/16/2008 2:45 PM (GMT -6)   
I just started it too.  Only been on it a week with a pred taper.  So far hasn't knocked out the flare.

Regular Member

Date Joined Mar 2007
Total Posts : 403
   Posted 4/16/2008 3:37 PM (GMT -6)   
It can take months to start working fully, and it will make you nauseous sometimes, so take it after a big meal.
12 Asacol
100 mg Imuran

Regular Member

Date Joined Mar 2008
Total Posts : 21
   Posted 4/16/2008 4:06 PM (GMT -6)   
I tried it for about 3 weeks back in the tail end of '06. It caused drug-induced hepatitis, so I had to get off it; but, it worked really well for those 3 weeks, and for several weeks after I stopped taking it. The two weeks of intense lower-chest pains from the hepatitis wasn't worth it, though.

If you start to get a pain that feels like it's originating behind the lower part of your sternum, talk to your doc asap; you might be starting up a hepatitis -- which would mean getting off the imuran.
Universal Colitis since 09/2003
Current Meds:
Asacol (1200mg 3x daily), [occationally alternate Asacol with Pentasa]
Prednisone (5mg, tapering),
VSL #3 (4 packet/day),
Calcium Supplement,

Regular Member

Date Joined Jun 2004
Total Posts : 123
   Posted 4/22/2008 11:18 AM (GMT -6)   
I will have been on Imuran for 1 year next month. Went to see my GI last week and she says that the Imuran appears to be working. I'm guessing, my lack of symptoms along with great monthly blood work gives us both hope.
Please ensure you go for the required, regular blood work.

February 04: Rushed to hospital with severe blood haemorrhage. Diagnosed with indeterminate UC in 2/3 of my bowel. Treated with heavy doses of Pred; started Salofalk tabs and sups.


April 06: First major flare – more haemorrhaging. Colonoscopy once against confirmed indeterminate UC.


May 06: Started 40 mg Pred. Weaned down to 10mg by July 8, held at 10mg until December 20, tapering 1mg every 2 weeks, 5mg a day as of February 14. All this plus 10 Salofalk tabs daily.


Jan through May 2007: Suffering from severe headaches and vomiting likely caused by prednisone.


Feb 26 07: Started Imuran with continued success.


May 12 07: Final dose of prednisone after 50 weeks!

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