Question for quincy

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Regular Member

Date Joined Sep 2007
Total Posts : 100
   Posted 4/22/2008 6:18 PM (GMT -6)   
Quincy, I know how much you recommend rectal meds and I finally got some. I have been in a flare for some time now, and have been taking lialda. That hasn't done a thing for me. Things seem to have actually gotten worse. Anyway, I went to see my GI yesterday and he had recommended imuran. He had mentioned it in the past but I wasn't too fond of the idea. We have tried many things to get this under control but have yet to be successful except for pred. But I seem to be steroid dependant, so he gave me three remicade infusions and that put me in total remission for a few months. Then back to flaring and have been for several months. Ok, to the point, he gave me a Rx for cortenema. Have you used this before? He told me to use it for 10 days. My sigmoidoscopy today showed that only my distal sigmoid colon and rectum were "messed up" right now. Last year it was throughout. Another question is if last year i had inflammation throughout, and now it is only towards the end of the intestines, can it all come back throughout again? I know I am full of questions, but I know how much you are for rectal meds and wanted your opinion on the cortenema. How do you use them. I guess I could wait and see what the instructions say, but didn't know if you had some advise on them. Sorry for the long post. Thanks for your help in advance :-)
29 Yrs old
Dx UC 3/07
4 Lialda/day
Remicade (only had three infusions)

Elite Member

Date Joined May 2003
Total Posts : 31006
   Posted 4/23/2008 1:26 AM (GMT -6)   
Hi....You've had the big guns before the first-line...interesting.

I've never used the cortenema, but others have and seem to have success with it.

It's liquid (60 ml) that's inserted in the rectum...the instructions will explain what to do with a picture (at least it's on the ones I use). You will have the feeling to expel it after it's in....squeeze your sphincter and just ride it out...the feeling will pass within the minute or so....although it'll feel like hours.

The doc says for you to use it for 10 days...then what? you should definitely be on the till you are having improvement..then taper them.
But that's a process...sometimes up and down..

The fact that most of your colon has improved is AWESOME!!! A good way to help keep the colon above the rectum calm is to remain on the Lialda. The reason you haven't had much success as you put's because you still have inflammation in the sigmoid/rectum.

What exactly are your symptoms by the way?

If you ignore your oral 5ASA meds, it's possible that it can spread upward again (since your initial diagnosis was throughout).
Doing the both ends approach helps deal with inflammation above and below the sigmoid/upper rectum.
I found this on Cortenema which will explain before you get the meds.

Let me know how it goes.



*Heather*Status: mini flare Dec 28... tapered to every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol (6 daily) + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~Probiotic 3(Natural Factors Protec) bedtime + 1 (Primadophilus Reuteri) occasionally
~multi-digestive enzymes as needed ....zymactive 3 - 5x daily
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!

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