I have had recent success with Humira, too, but just had my dose increased to weekly, to try and get me to remission finally.
I totally agree with the above tips, and even though I was reluctant to try injections in the stomach, they are MUCH less uncomfortable than the thighs -- more fatty tissue. Now that I have been doing this for a few months, I can handle alternating with the thighs with less discomfort.
I would recommend having someone else administer the shots for you. The burn is intense, and I think I would not be able to hold the pen in place for the full 10 seconds. It helps to have someone firmly but gently do it for you.
My experience was that while I saw nearly immediate results with Remicade, it took me 4 weeks to see results with Humira (which is exactly what the fine print reads, incidentally), so don't get despondent if it takes a while to kick in.
Best of luck -- hope you have good results!
Dx Mild Proctitis 7/06 at age 33, Dx Severe Pan Colitis 5/07, Dx Crohn's Colitis 10/07
Failed Asacol, Lialda, 6-MP, Canasa, Rowasa, Entocort, and Remicade
On Humira since 1/08 with promising results, but can't get below 5mg Prednisone
Take Tylenol #3 as needed when not in close proximity to a bathroom.
Currently on 40mg Prednisone again since mid-March flare, ack
4/9/08 Humira dose increased to 40mg/week, Start slow Pred taper