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billo
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Date Joined Mar 2006
Total Posts : 568
   Posted 4/28/2008 10:19 PM (GMT -6)   
I heard recently that due to gene therapy, scientists have been able to restore sight to a few hundred blind people that suffered from a condition (i forgot the name of the condition) its been all over the news.

I wonder if gene therapy can work w/ u.c.?

GardenerJames
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Date Joined Jan 2006
Total Posts : 616
   Posted 4/28/2008 10:29 PM (GMT -6)   
I've heard that gene therapy has been effective in some other inflammatory conditions, so that's a good sign for us too!
Asacol 4 tabs 2x daily www.myspace.com/gardenerjames
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pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20577
   Posted 4/29/2008 12:00 AM (GMT -6)   

Wonder no more, check out this link...you may have to copy and paste it into your search engine if clicking on it doesn't work...

 

 

 
 
:)
My bum is broken....there's a big crack down the middle of it!  LOL  :)


billo
Veteran Member


Date Joined Mar 2006
Total Posts : 568
   Posted 4/29/2008 7:11 AM (GMT -6)   
thanks for the link, but did it really say 2003 as the date?

pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20577
   Posted 4/29/2008 12:13 PM (GMT -6)   

Yes, 2003...they've been looking not this kind of treatment for many yrs...I've read somewhere that they've tested stem cell therapy on many IBD patients.

 

Here's a 2007 article;

 

http://www.sciencedaily.com/releases/2007/11/071130223834.htm

 

 

:)


My bum is broken....there's a big crack down the middle of it!  LOL  :)


billo
Veteran Member


Date Joined Mar 2006
Total Posts : 568
   Posted 4/29/2008 2:08 PM (GMT -6)   
interesting.... its for crohns but i imagine it wouldnt be very far off for a u.c. version of this stem cell stuff?

btw the article mentioned how scientists believe what sets crohns off is interaction w/ an environmental stimulus. I imagine u.c. is the same way, and once you're exposed to said stimulus, how long before you show symptoms of the disease? a month? a year?

pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20577
   Posted 4/29/2008 3:52 PM (GMT -6)   
Since UC is also basically the same disease as crohns (inflammatory bowel disease) I'm sure the stem cell therapy used for CD as mentioned in the article would work the same for UC.

That would be the trigger you're referring to, it's the same with UC, IBD is basically a genetic disease that needs to be triggered in order for one with IBD to become sick...it's anyone's guess how long it can take once it's been triggered for symptoms to appear...so I wouldn't invest too much time trying to figure out what triggered your disease...it's also known that smoking is a trigger for crohns disease, yet for UC it can keep it at bay until one quits smoking, but that's not written in stone either, lots of people who smoke still get UC even without quitting first and lots of people with CD can do fine smoking compared to not (I'm living proof, I did much worse with my CD when I quit smoking for 3 yrs compared to when I started again, maybe because my CD is affecting my colon, who knows) although it's estimated that CDers who smoke will have more relaps with disease affecting their small intestines, which has not happend to me...I only had it affecting my small intestines 17 yrs ago when I first got CD and it was also affecting my colon and anus then too, it cleared up (somehow) in my small intestines but has remained in my colon and anus and has come and gone over the 17yrs in my rectom as well.

:)
My bum is broken....there's a big crack down the middle of it!  LOL  :)


billo
Veteran Member


Date Joined Mar 2006
Total Posts : 568
   Posted 4/29/2008 4:12 PM (GMT -6)   
i know it sounds like a fantasy, but if the disease can be 'triggered' i believe it could also be 'detriggered' like go away (remission) - but for good :)

pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20577
   Posted 4/29/2008 6:36 PM (GMT -6)   
Researchers have not found an answer to that simply because they believe there are many possibilities of environmental triggers out there, so the stem cell is the best route.

:)
My bum is broken....there's a big crack down the middle of it!  LOL  :)


pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20577
   Posted 4/29/2008 7:24 PM (GMT -6)   
Not to mention, it could very well be a combination of triggers of which one would likely never be able to figure out in their life time to "de-trigger" it.

check out this link...from the CCFC, even they don't rule out food completely as being a possible trigger simply because not enough is know overall about IBD...
 
 
 
:)


My bum is broken....there's a big crack down the middle of it!  LOL  :)


Red_34
Elite Member


Date Joined Apr 2004
Total Posts : 23551
   Posted 4/29/2008 8:48 PM (GMT -6)   
Billo, I want to join your fantasy world.  If I think real hard, do you think I can manage to turn off my Uc? (J/K) tongue    I see so much possibilities in the future but what are the chances that we will see them in our lifetime?  But you know what? Now that I think about it - I've had Uc for 16 years.  16 years ago, they didn't even know what triggers Uc let alone any gene component to it.  I remember when I was first diagnosed, I had to fill out a survey.  And it had some pretty strange questions on it.  But the hospital I was at, was a major teaching hospital and top of it's league in research.  But who knows? Maybe in the near future we will see a cure!
 @--->--SHERRY--<---@
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~Left sided Uc-'92-Colazal(9 daily),6mp(50-100mgs),Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate Asacol, Rowasa or Canasa**~Allergies-Singulair
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billo
Veteran Member


Date Joined Mar 2006
Total Posts : 568
   Posted 4/30/2008 3:55 PM (GMT -6)   
hey red, sorry to hear about 16 years, i've had u.c. for 2 1/2 years... and feel its unfair that i cant drink anymore and eat popcorn at the movies w/o having serious issues the following day, not to mention worrying to take my meds, grrrr... I'm 28 and HOPEFULLY they will have a cure in my lifetime, even if they find a cure when i'm in my 50's would be awesome as heck.

my mom is 58 and recently diagnosed w/ rheumatoid arthritis, and complained to me, and not to be rude to her, but i said, "listen you got to be healthy for over 57 years w/o any incident, (chicken pox) -THATS IT! i told her she has no room to ***** to me about health issues.

*interesting about rheumatoid, her doctor told her that rheumatoid is not that different from u.c. and sulfasalazine (which i'm taking) is also prescribed for R.A.

Red_34
Elite Member


Date Joined Apr 2004
Total Posts : 23551
   Posted 4/30/2008 4:46 PM (GMT -6)   
I know what you mean. My grandmother who has been healthy for 86 years just recently started complaining about her eye sight going, her mental status going, and her 4 pills a day she has to take since the last 2 years. Of course I don't say anything, but I was biting at the bit. I was diagnosed at 22 so I don't know much of anything else but having Uc and everything it entails. Man if I could be so lucky as to have no major health problems for 86 years!

And yes, I heard about the Sulfasalazine being used in RA. It's like killing 2 birds with one stone!
 @--->--SHERRY--<---@
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc-'92-Colazal(9 daily),6mp(50-100mgs),Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate Asacol, Rowasa or Canasa**~Allergies-Singulair
~Secondary Reynauds Syndrome-'04-Norvasc~Spinal Stenosis~Sacroiliitis-epidural injections
To help Healingwell - click here: DONATE
 
 
 
 

 
 

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