Not sure about the imodium, but if I was in a medium or bad flare and using lomotil I may wake up and take 2 a couple of hours before leaving, then another one half way there.
I have a pre-trip routine anytime I am gonna be in the car for more than an hour. I HATE TRAVELING IN THE MORNINGS, but if I do I give myself 3 hours wakeup/bathroom/me time. If I have to be somewhere at 7am, I am up at 4am. I eat something light as soon as my feet hit the floor, after a bm or two I may use a little of a hydrocort enema to soothe any inflammation. I take a lomotil 1 1/2 hour before leaving. No food during car trip unless its just a good day and I haven't had alot of problems recently. Lomotil 4 hours in. I live in Dickson Tennessee, so I'll be traveling 7 1/2 hours to WV over upcoming holiday weekend.
Proctitis DX 1998
Lialda 1x day
Hydrocort Enema As Needed