Welcome to HealingWell.
Oral 5-ASA medications such as Colazal are released in the colon, and often used up before they reach the rectal area. Since they are actually topical, working through contact with the bowel wall rather than by being delivered through the bloodstream, this means the upper colon is being treated but the rectal-sigmoid area really isn't being treated. Adding a 5-ASA enema provides the same treatment to the lower colon that oral meds provide to the rest of the colon.
Also, some of us do find that 9 Colazal a day will cause looser stools, while cutting back to 6 still controls the flaring without the loose stools. If you want to try this, decrease the dose gradually, dropping one capsule every couple of weeks to see how you do.
Are you on any probiotic? Probiotics are preparations of beneficial bacteria that inhabit normal, healthy colons. When we get UC, these tend to get stripped out of our colons, leading to more bowel dysfunction. You should be able to get a good quality probiotic at any health store or pharmacy. I take Primadophilus Reuteri by Nature's way. Other popular preparations are Culturelle and VSL#3. Often these will help with stool quality.
My final suggestion would be to try adding some good soluble fiber to your diet to see if that helps. You can get it with cooked fruits and vegetables, but it's easier to take a supplement - Metamucil, Fiber-con or the like.
I hope you're soon feeling better. Keep us posted!
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Asacol, Rowasa, Pentasa, Prednisone, Entocort, Azathioprine
Avascular necrosis in both shoulders is my "forever" gift from steroid therapy.
Colazal, Remicade, Nature's Way Primadophilus Reuteri. In remission since April, 2006.
Co-Moderator UC Forum
Please remember to consult your health care provider when making health-related decisions.