pred again - how long can it take to kick in?

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hana24
Regular Member


Date Joined Dec 2007
Total Posts : 354
   Posted 5/21/2008 1:33 PM (GMT -6)   
My doctor put me on a 40 mg taper and it has been two days and I am not getting better. Last time I felt better in a couple of hours. I have been bleeding alot for the last week or so. I am concerned because I am supposed to go on vacation on Sunday. Should I ask to go to a higher dose? I have never bled this much in my life. I have been getting up all night every two hours or so. Any ideas?
Jessica 26/F On Entorcout again...
dicyclomine 10Mg before bed
Citalopram 20 MG
Colazal 3X3/day
Culturelle once daily
omeprazole(for acid reflex)
Tried (Entorcort EC 9ml/day and Prednisone, Asacol)


Beth75
Veteran Member


Date Joined Jul 2007
Total Posts : 2148
   Posted 5/21/2008 1:39 PM (GMT -6)   
It took about 2 months for me.........the steriod e's helped me much quicker.
Beth, 32 ~ small flare - hoping caused by aspirin
Major Flare Sept/Oct 07
UC dx'd 03/00 (Proctosigmoiditis); Pancolitis since 09/07
Azathioprine 200mg 1xday nightly; Calcium and Vit D 500mg 3xday, Multi Vit, Folic Acid 400mg 2xday, Prilosec, Probiotics.
Minimal Change Disease (Kidney Disorder) dx'd 09/07 - partial remission since 03/08
Prednisone 5mg 1xday (tapered from 60 = ), Simvastatin 20mg 1xday, Diovan 160mg 2xday. Enalapril 20mg 1xday, Fosomax 70mg 1xweek. MCD may be from hypersensitivty to 5ASA drugs.  Do you have edema? If so, check your blood protien level!
 


munchkindd
Regular Member


Date Joined Oct 2007
Total Posts : 348
   Posted 5/21/2008 1:40 PM (GMT -6)   
If I remember right, it took me around 4 or 5 days to see some improvment with pred. But, then again, everybody is different. Are you currently doing the entocort?? Good Luck
*******Donna*******
 
diagnosed with uc 27 years ago.  Enojoyed 20 year remission with just minor blips here and there (approximately 16 of those years without any meds)
 
In a flare for 2 very long years which Asacol didn't help at all.  Finally in remission again since Jan 2008, can't believe it..............
 
currently on Sulfasalazine 2 tabs 3x day. Folic acid, mesalamine enema 2 x a week. Omega 3, Probiotics, multi vitamin, cacium supplement, Biotin....
 


tums
Regular Member


Date Joined Apr 2008
Total Posts : 128
   Posted 5/21/2008 1:57 PM (GMT -6)   
I have just come out of a flare. It took me 3 weeks at 40mg to get things under control then I tapered by 5 mg per week, down to 15mg on Friday fingers crossed all keeps going well.

32 year old female
UC diagnosed 2001
Asacol 6 per day
Azathioprine 50mg started 4/08
Steroids 40mg per day


expecting226
Regular Member


Date Joined Jul 2007
Total Posts : 402
   Posted 5/21/2008 2:02 PM (GMT -6)   
Each time I do a taper of Prednisone, it takes a bit longer to work. On average, it takes about a week for me. The first time, it took 2 days. The last time, it took 8 days.

Hang in there and give it a bit more time. If you aren't better in 7-10 days, I would give your doc a call.
Proud new mom of a beautiful baby boy!
Current Medications:
- Asacol (4 pills, 3x per day)
- Rowasa (1 enema daily, as needed)
- Folic Acid (1 mg, 1x per day)
- Calcium (600 mg, 2x per day)
- Prenatal Vitamin (1x per day)


hana24
Regular Member


Date Joined Dec 2007
Total Posts : 354
   Posted 5/21/2008 6:03 PM (GMT -6)   
Thank you all for your replys - I am just stressing about it. I am just hoping I am better before my flight on Sunday. I stopped the entocort when I started the pred. The entocort works perfect for me for a couple of weeks and then it just quits.
Jessica 26/F On Entorcout again...
dicyclomine 10Mg before bed
Citalopram 20 MG
Colazal 3X3/day
Culturelle once daily
omeprazole(for acid reflex)
Tried (Entorcort EC 9ml/day and Prednisone, Asacol)


tjf
Veteran Member


Date Joined Dec 2005
Total Posts : 3238
   Posted 5/21/2008 6:27 PM (GMT -6)   
The first time I flared 40mg kicked in quickly. The second flare I had to go up to 60mg to get the same effectiveness. Have you asked if there is another rectal med you can do in addition to the pred?
Tabitha (Tab)

100mg Azathioprine, 2 Fibercon, Colazal-9 a day, Acidopholis Pearls, Nexium

http://www.healingwell.com/donate
Co-Moderator UC Forum


munchkindd
Regular Member


Date Joined Oct 2007
Total Posts : 348
   Posted 5/21/2008 6:30 PM (GMT -6)   
how about cortenemas?
*******Donna*******
 
diagnosed with uc 27 years ago.  Enojoyed 20 year remission with just minor blips here and there (approximately 16 of those years without any meds)
 
In a flare for 2 very long years which Asacol didn't help at all.  Finally in remission again since Jan 2008, can't believe it..............
 
currently on Sulfasalazine 2 tabs 3x day. Folic acid, mesalamine enema 2 x a week. Omega 3, Probiotics, multi vitamin, cacium supplement, Biotin....
 


TraciZ
Regular Member


Date Joined Aug 2007
Total Posts : 255
   Posted 5/21/2008 6:39 PM (GMT -6)   
omg. I bet the stressing about vacation isn't helping either! I don't have any suggestions, but want you to know that I hope you feel better! Where are you going on vacation, btw?
Tressa 34 (F)
Not sure of my dx- currently UC, but with skip lesions. Bloodwork is inconclusive for UC & Crohn's. Colonoscopy shows ulceration in terminal ileum and descending colon
Colazal 3X3/day
Lialda upped to 4/day,
Colazal 3X3/day
Phosphatidylcholine 4 (420 mg capsules) once/day


ddneilson
Regular Member


Date Joined Mar 2008
Total Posts : 21
   Posted 5/21/2008 9:42 PM (GMT -6)   
I've had it take anywhere from overnight to 3 weeks for the pred to start making a difference. As with darn near everything else with this silly disease, it seems completely random to me.
Universal Colitis since 09/2003
Current Meds:
Asacol (800mg 3x daily),
Prednisone (40mg/day) again <sigh>,
VSL #3 (2-4 packet/day),
Calcium Supplement,
Multivitamin


hana24
Regular Member


Date Joined Dec 2007
Total Posts : 354
   Posted 5/22/2008 7:01 AM (GMT -6)   
I'm going to california to visit my parents for a week. At least they have two bathrooms:) I was literly up all night every 45 mins to an hour going to the bathroom. I have never been this bad how likely is it that the Colazal could be causing it? I have been on it for two weeks. I switched from asacol.

My doctor said that rectal meds will not help because I didn't have inflammation in my rectum but I wonder if I do now. Sometimes I feel like I have to go and nothing will come out or just a little blood. Does anyone know if this means my rectum is inflamed? I have some steroid suppositories that he gave me for a hemmi. Would those help?
Jessica 26/F On Entorcout again...
dicyclomine 10Mg before bed
Citalopram 20 MG
Colazal 3X3/day
Culturelle once daily
omeprazole(for acid reflex)
Tried (Entorcort EC 9ml/day and Prednisone, Asacol)


expecting226
Regular Member


Date Joined Jul 2007
Total Posts : 402
   Posted 5/22/2008 8:49 AM (GMT -6)   
The Colazal could be causing it. Did the D start after you switched over from Asacol?
Proud new mom of a beautiful baby boy!
Current Medications:
- Asacol (4 pills, 3x per day)
- Rowasa (1 enema daily, as needed)
- Folic Acid (1 mg, 1x per day)
- Calcium (600 mg, 2x per day)
- Prenatal Vitamin (1x per day)


hana24
Regular Member


Date Joined Dec 2007
Total Posts : 354
   Posted 5/22/2008 8:58 AM (GMT -6)   
Yes, but I can't tell it my flair was just getting worse or if it could be from the colazal. I didn't feel like the asacol was helping and it doesn't seem to keep me in remission so I thought I should switch my maintaince drug before going on pred but now I don't know what to do. I feel worse than I have ever felt before. I am seeing a little less blood since the pred but its very much still there and I am going to the bathroom 15-20 times. It seems a little more solid this morning.
Jessica 26/F On Entorcout again...
dicyclomine 10Mg before bed
Citalopram 20 MG
Colazal 3X3/day
Culturelle once daily
omeprazole(for acid reflex)
Tried (Entorcort EC 9ml/day and Prednisone, Asacol)


neondream
Regular Member


Date Joined May 2008
Total Posts : 47
   Posted 5/22/2008 1:18 PM (GMT -6)   
I know how you feel, i started having a flare up a couple days ago and im waiting for the prednisone to do its job as well. I have a flight to san francisco tomorrow and im pretty sure im not going to go. You still have a couple days left so hang in there!
20. Female. California.
Diagnosed left sided Ulcerative Colitis at 15, first symptoms at age 11.
5mg prednisone daily. (now taking 20mg for flare)
Aloe Vera 3x daily
Fish Oil 3x daily.


hana24
Regular Member


Date Joined Dec 2007
Total Posts : 354
   Posted 5/22/2008 8:27 PM (GMT -6)   
thank you all for responding. He is fitting me in tommorow afternoon before my trip hopefully I can find a solution. I am going to be out of luck if pred wont even make me fell better. I might try stopping the colazal.
Jessica 26/F 40mg pred taper
dicyclomine 10Mg before bed
Citalopram 20 MG
Colazal 3X3/day
Culturelle once daily
omeprazole(for acid reflex)
Tried (Entorcort EC 9ml/day and Prednisone, Asacol)

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