I have been in two different clinical studies. Both were Phase 3 double blind placebo controlled studies. Not all studies use placebos. There are 4 phases. More information about each phase can be found at:
Phase 3 is the phase just before approval and I recommend you stick with them. They have already had phase 1 and 2 testing which means some information is already available as to safety and effectiveness. Also if they work for you, you will most likely be able to continue on the treatment at no cost until it is approved. After that your insurance should cover it. It could take a few years to be approved. A good article about “Understanding Clinical Trials” can be found at:
Don’t let the chance of receiving the placebo bother you. If the initial stage of the trial does not produce results you will be given the real treatment. There should be no cost to you for the medications, scopes including prep or lab work. I found I got much better attention from my GI when I was in the studies then when I was just another patient. I had easier access and more time devoted to me then normal. Study patients get higher priority. Both studies I was paid $20.00 for each visit whether it was for a scope, treatment, lab work or physical checkup. Not enough to get rich on but it did cover my transportation and lunch. Unfortunately neither study helped me and I am now considering surgery.
Diagnosed in 2000 at age 43 with UC extending half way across transverse colon.
Bad reaction to Asacol, Pentasa and Dipentum - can’t take any more 5ASAs.
Prednisone - worked well for 1 month, then side effects became unbearable.
6-MP - blood tests showed not metabolizing properly.
Corticosteroid enema, Flagyl, Ciprofloxin, VSL#3, Adacolumn Apheresis – no effect
Methotrexate with Remicade - 7 infusions with no improvement
Folic Acid and B12 injections.
Abatacept trial - no effect