I'm severly allergic to 5-ASA's and my dr. took me off of them. I visited with him the other day and he wants me to try the Nicotine Patch since I'm a former smoker. He told me if that doesn't work we'll try the Avandia (which is a diabetes medication). However, back in January there were problems with Avandia with increased cardiovascular disease but from what I understand there has been several research studies that have vindicated that. My dr. is adominantly against putting me on steriods due to it's huge profile of side effects. Talk to your dr. and see what your options are....every dr. is different. My previous dr. wanted to put me on prednisone right away several times and my new dr. only wants to use them as a last resort. good luck!